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MGI:Fgf18
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Fgf18 ( synonyms: FGF-18 ) | |
| Protein Name(s) | fibroblast growth factor 18, | |
| External Links | ||
| MGI | MGI:1277980 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001503 |
ossification |
MGI:MGI:2177990 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2178751 |
P |
From MGI |
||
| GO:0001503 |
ossification |
MGI:MGI:2177991 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2179607 |
P |
From MGI |
||
| GO:0001525 |
angiogenesis |
MGI:MGI:3703411 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2178751 |
P |
From MGI |
||
| GO:0001957 |
intramembranous ossification |
MGI:MGI:3703411 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2178751 |
P |
From MGI |
||
| GO:0001958 |
endochondral ossification |
MGI:MGI:3703411 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2178751 |
P |
From MGI |
||
| GO:0002063 |
chondrocyte development |
MGI:MGI:3703411 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2178751 |
P |
From MGI |
||
| GO:0005104 |
fibroblast growth factor receptor binding |
MGI:MGI:2177990 |
TAS: Traceable Author Statement |
F |
From MGI |
|||
| GO:0005105 |
type 1 fibroblast growth factor receptor binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005111 |
type 2 fibroblast growth factor receptor binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005576 |
extracellular region |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0964 |
C |
From MGI |
||
| GO:0005730 |
nucleolus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0007165 |
signal transduction |
MGI:MGI:2177990 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0007399 |
nervous system development |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0008083 |
growth factor activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0339 |
F |
From MGI |
||
| GO:0008083 |
growth factor activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0008284 |
positive regulation of cell proliferation |
MGI:MGI:3703411 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2178751 |
P |
From MGI |
||
| GO:0008543 |
fibroblast growth factor receptor signaling pathway |
MGI:MGI:3584218 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:95524 |
P |
From MGI |
||
| GO:0030324 |
lung development |
MGI:MGI:3051435 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2179607 |
P |
From MGI |
||
| GO:0030949 |
positive regulation of vascular endothelial growth factor receptor signaling pathway |
MGI:MGI:3703411 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2178751 |
P |
From MGI |
||
| GO:0032332 |
positive regulation of chondrocyte differentiation |
MGI:MGI:3584218 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:95524 |
P |
From MGI |
||
| GO:0070374 |
positive regulation of ERK1 and ERK2 cascade |
MGI:MGI:2175916 |
IDA: Inferred from Direct Assay |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Liu Z et al. (2002) Coordination of chondrogenesis and osteogenesis by fibroblast growth factor 18. Genes Dev 16: 859-69 PubMed GONUTS page
- ↑ Ohbayashi N et al. (2002) FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis. Genes Dev 16: 870-9 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 Liu Z et al. (2007) FGF18 is required for early chondrocyte proliferation, hypertrophy and vascular invasion of the growth plate. Dev Biol 302: 80-91 PubMed GONUTS page
- ↑ 4.0 4.1 Davidson D et al. (2005) Fibroblast growth factor (FGF) 18 signals through FGF receptor 3 to promote chondrogenesis. J Biol Chem 280: 20509-15 PubMed GONUTS page
- ↑ Usui H et al. (2004) Fgf18 is required for embryonic lung alveolar development. Biochem Biophys Res Commun 322: 887-92 PubMed GONUTS page
- ↑ Shimoaka T et al. (2002) Regulation of osteoblast, chondrocyte, and osteoclast functions by fibroblast growth factor (FGF)-18 in comparison with FGF-2 and FGF-10. J Biol Chem 277: 7493-500 PubMed GONUTS page
