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MGI:Fgf1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Fgf1 ( synonyms: Fgf-1, Fgfa, fibroblast growth factor 1 (acidic) )
Protein Name(s) fibroblast growth factor 1,
External Links
MGI MGI:95515

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001525

angiogenesis

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0037

P

From MGI

GO:0001759

organ induction

MGI:MGI:3511765
PMID:15576401[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0001934

positive regulation of protein phosphorylation

MGI:MGI:3578606
PMID:15800000[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0005104

fibroblast growth factor receptor binding

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:P05230

F

From MGI

GO:0005104

fibroblast growth factor receptor binding

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:P05230

F

From MGI

GO:0005515

protein binding

MGI:MGI:3807762
PMID:16263090[3]

IPI: Inferred from Physical Interaction

UniProtKB:P15880

F

From MGI

GO:0005576

extracellular region

MGI:MGI:3838658
PMID:19233122[4]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005576

extracellular region

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P05230

C

From MGI

GO:0005578

proteinaceous extracellular matrix

MGI:MGI:3525426
PMID:15381701[5]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005615

extracellular space

MGI:MGI:3511765
PMID:15576401[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005615

extracellular space

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P05230

C

From MGI

GO:0005634

nucleus

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P61149

C

From MGI

GO:0005730

nucleolus

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P61149

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P61149

C

From MGI

GO:0005829

cytosol

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P05230

C

From MGI

GO:0007275

multicellular organismal development

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0217

P

From MGI

GO:0008083

growth factor activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P61149

F

From MGI

GO:0008083

growth factor activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P05230

F

From MGI

GO:0008201

heparin binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P05230

F

From MGI

GO:0008284

positive regulation of cell proliferation

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:P05230

P

From MGI

GO:0008284

positive regulation of cell proliferation

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:P05230

P

From MGI

GO:0008543

fibroblast growth factor receptor signaling pathway

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:P05230

P

From MGI

GO:0008543

fibroblast growth factor receptor signaling pathway

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:P05230

P

From MGI

GO:0008543

fibroblast growth factor receptor signaling pathway

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:P05230

P

From MGI

GO:0010740

positive regulation of intracellular protein kinase cascade

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P05230

P

From MGI

GO:0030154

cell differentiation

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0221

P

From MGI

GO:0030324

lung development

MGI:MGI:3511765
PMID:15576401[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0030335

positive regulation of cell migration

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P05230

P

From MGI

GO:0034605

cellular response to heat

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P05230

P

From MGI

GO:0044548

S100 protein binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P05230

F

From MGI

GO:0045542

positive regulation of cholesterol biosynthetic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P05230

P

From MGI

GO:0045766

positive regulation of angiogenesis

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P05230

P

From MGI

GO:0045893

positive regulation of transcription, DNA-dependent

MGI:MGI:4943617
PMID:20299672[6]

TAS: Traceable Author Statement

P

From MGI

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P05230

P

From MGI

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

MGI:MGI:83672
PMID:8898217[7]

IGI: Inferred from Genetic Interaction

MGI:MGI:97168

P

From MGI

GO:0050679

positive regulation of epithelial cell proliferation

MGI:MGI:3701403
PMID:17187775[8]

IDA: Inferred from Direct Assay

P

From MGI

GO:0051781

positive regulation of cell division

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P05230

P

From MGI

GO:0060038

cardiac muscle cell proliferation

MGI:MGI:4943617
PMID:20299672[6]

TAS: Traceable Author Statement

P

From MGI

GO:0060681

branch elongation involved in ureteric bud branching

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P05230

P

From MGI

GO:0060979

vasculogenesis involved in coronary vascular morphogenesis

MGI:MGI:4943617
PMID:20299672[6]

TAS: Traceable Author Statement

P

From MGI

GO:0072163

mesonephric epithelium development

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P05230

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Serls AE et al. (2005) Different thresholds of fibroblast growth factors pattern the ventral foregut into liver and lung. Development 132: 35-47 PubMed GONUTS page
  2. Mailleux AA et al. (2005) Fgf10 expression identifies parabronchial smooth muscle cell progenitors and is required for their entry into the smooth muscle cell lineage. Development 132: 2157-66 PubMed GONUTS page
  3. Antoine M et al. (2005) Fibroblast growth factor 3, a protein with a dual subcellular fate, is interacting with human ribosomal protein S2. Biochem Biophys Res Commun 338: 1248-55 PubMed GONUTS page
  4. Graziani I et al. (2009) Protein folding does not prevent the nonclassical export of FGF1 and S100A13. Biochem Biophys Res Commun 381: 350-4 PubMed GONUTS page
  5. Jasuja R et al. (2004) Cell-surface heparan sulfate proteoglycans potentiate chordin antagonism of bone morphogenetic protein signaling and are necessary for cellular uptake of chordin. J Biol Chem 279: 51289-97 PubMed GONUTS page
  6. 6.0 6.1 6.2 Olivey HE & Svensson EC (2010) Epicardial-myocardial signaling directing coronary vasculogenesis. Circ Res 106: 818-32 PubMed GONUTS page
  7. Chen Y et al. (1996) Msx1 controls inductive signaling in mammalian tooth morphogenesis. Development 122: 3035-44 PubMed GONUTS page
  8. van Tuyl M et al. (2007) Angiogenic factors stimulate tubular branching morphogenesis of sonic hedgehog-deficient lungs. Dev Biol 303: 514-26 PubMed GONUTS page
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