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MGI:Fen1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Fen1 | |
| Protein Name(s) | flap structure specific endonuclease 1, | |
| External Links | ||
| MGI | MGI:102779 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000287 |
magnesium ion binding |
MGI:MGI:2183876 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003677 |
DNA binding |
MGI:MGI:2183876 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003677 |
DNA binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0004519 |
endonuclease activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0255 |
F |
From MGI |
||
| GO:0004523 |
ribonuclease H activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0004527 |
exonuclease activity |
MGI:MGI:2183876 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:2183876 |
TAS: Traceable Author Statement |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005739 |
mitochondrion |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006260 |
DNA replication |
MGI:MGI:2668283 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2670036 |
P |
From MGI |
||
| GO:0006281 |
DNA repair |
MGI:MGI:2668283 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2670036 |
P |
From MGI |
||
| GO:0008409 |
5'-3' exonuclease activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0017108 |
5'-flap endonuclease activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0030145 |
manganese ion binding |
MGI:MGI:2183876 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0043137 |
DNA replication, removal of RNA primer |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0048256 |
flap endonuclease activity |
MGI:MGI:2183876 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0090305 |
nucleic acid phosphodiester bond hydrolysis |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0255 |
P |
From MGI |
||
| GO:0090305 |
nucleic acid phosphodiester bond hydrolysis |
MGI:MGI:2183876 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0090305 |
nucleic acid phosphodiester bond hydrolysis |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Zheng L et al. (2002) Distinct roles of two Mg2+ binding sites in regulation of murine flap endonuclease-1 activities. Biochemistry 41: 10323-31 PubMed GONUTS page
- ↑ 2.0 2.1 Larsen E et al. (2003) Proliferation failure and gamma radiation sensitivity of Fen1 null mutant mice at the blastocyst stage. Mol Cell Biol 23: 5346-53 PubMed GONUTS page
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