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MGI:Fcgr1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Fcgr1 ( synonyms: CD64, FcgammaRI ) | |
| Protein Name(s) | Fc receptor, IgG, high affinity I, | |
| External Links | ||
| MGI | MGI:95498 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001788 |
antibody-dependent cellular cytotoxicity |
MGI:MGI:2664488 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2664927 |
P |
From MGI |
||
| GO:0001788 |
antibody-dependent cellular cytotoxicity |
MGI:MGI:2679189 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2679238 |
P |
From MGI |
||
| GO:0001798 |
positive regulation of type IIa hypersensitivity |
MGI:MGI:2664488 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2664927 |
P |
From MGI |
||
| GO:0001805 |
positive regulation of type III hypersensitivity |
MGI:MGI:2679189 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2679238 |
P |
From MGI |
||
| GO:0004872 |
receptor activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0675 |
F |
From MGI |
||
| GO:0005886 |
plasma membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006898 |
receptor-mediated endocytosis |
MGI:MGI:2679189 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2679238 |
P |
From MGI |
||
| GO:0006910 |
phagocytosis, recognition |
MGI:MGI:2664488 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2664927 |
P |
From MGI |
||
| GO:0006910 |
phagocytosis, recognition |
MGI:MGI:2679188 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2679238 |
P |
From MGI |
||
| GO:0006910 |
phagocytosis, recognition |
MGI:MGI:2679189 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2679238 |
P |
From MGI |
||
| GO:0006911 |
phagocytosis, engulfment |
MGI:MGI:2664488 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2664927 |
P |
From MGI |
||
| GO:0006911 |
phagocytosis, engulfment |
MGI:MGI:2679188 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2679238 |
P |
From MGI |
||
| GO:0006911 |
phagocytosis, engulfment |
MGI:MGI:2679189 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2679238 |
P |
From MGI |
||
| GO:0007166 |
cell surface receptor signaling pathway |
MGI:MGI:2664488 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2664927 |
P |
From MGI |
||
| GO:0007166 |
cell surface receptor signaling pathway |
MGI:MGI:2679188 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2679238 |
P |
From MGI |
||
| GO:0007166 |
cell surface receptor signaling pathway |
MGI:MGI:2679189 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2679238 |
P |
From MGI |
||
| GO:0009617 |
response to bacterium |
MGI:MGI:3699739 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2664927 |
P |
From MGI |
||
| GO:0009897 |
external side of plasma membrane |
MGI:MGI:2679189 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From MGI |
||
| GO:0019770 |
IgG receptor activity |
MGI:MGI:2664488 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2664927 |
F |
From MGI |
||
| GO:0019770 |
IgG receptor activity |
MGI:MGI:2679188 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2679238 |
F |
From MGI |
||
| GO:0019770 |
IgG receptor activity |
MGI:MGI:2679189 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2679238 |
F |
From MGI |
||
| GO:0019864 |
IgG binding |
MGI:MGI:2664488 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2664927 |
F |
From MGI |
||
| GO:0019864 |
IgG binding |
MGI:MGI:2679188 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0019864 |
IgG binding |
MGI:MGI:2679189 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2679238 |
F |
From MGI |
||
| GO:0019884 |
antigen processing and presentation of exogenous antigen |
MGI:MGI:2679189 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2679238 |
P |
From MGI |
||
| GO:0042590 |
antigen processing and presentation of exogenous peptide antigen via MHC class I |
MGI:MGI:2664488 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2664927 |
P |
From MGI |
||
| GO:0042742 |
defense response to bacterium |
MGI:MGI:2664488 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2664927 |
P |
From MGI |
||
| GO:0045087 |
innate immune response |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0399 |
P |
From MGI |
||
| GO:0050766 |
positive regulation of phagocytosis |
MGI:MGI:2664488 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2664927 |
P |
From MGI |
||
| GO:0050766 |
positive regulation of phagocytosis |
MGI:MGI:2679188 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2679238 |
P |
From MGI |
||
| GO:0050766 |
positive regulation of phagocytosis |
MGI:MGI:2679189 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2679238 |
P |
From MGI |
||
| GO:0050776 |
regulation of immune response |
MGI:MGI:2664488 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2664927 |
P |
From MGI |
||
| GO:0050776 |
regulation of immune response |
MGI:MGI:2679189 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2679238 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 Ioan-Facsinay A et al. (2002) FcgammaRI (CD64) contributes substantially to severity of arthritis, hypersensitivity responses, and protection from bacterial infection. Immunity 16: 391-402 PubMed GONUTS page
- ↑ 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 Barnes N et al. (2002) FcgammaRI-deficient mice show multiple alterations to inflammatory and immune responses. Immunity 16: 379-89 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 Gavin AL et al. (1998) Identification of the mouse IgG3 receptor: implications for antibody effector function at the interface between innate and adaptive immunity. J Immunol 160: 20-3 PubMed GONUTS page
- ↑ Uppington H et al. (2006) Effect of immune serum and role of individual Fcgamma receptors on the intracellular distribution and survival of Salmonella enterica serovar Typhimurium in murine macrophages. Immunology 119: 147-58 PubMed GONUTS page
