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MGI:Fcer2a

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Fcer2a ( synonyms: CD23, FC epsilon RII, Fce2, low-affinity IgE receptor, Ly-42 )
Protein Name(s) Fc receptor, IgE, low affinity II, alpha polypeptide,
External Links
MGI MGI:95497

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0002925

positive regulation of humoral immune response mediated by circulating immunoglobulin

MGI:MGI:67606
PMID:8041705[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3583003

P

From MGI

GO:0004872

receptor activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0675

F

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:1889050
PMID:8418208[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:2670820
PMID:12882831[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:3028699
PMID:14662849[4]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:3581459
PMID:15909309[5]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:3640996
PMID:11435465[6]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:67606
PMID:8041705[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:77753
PMID:8566034[7]

IDA: Inferred from Direct Assay

C

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016021

integral to membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0812

C

From MGI

GO:0019863

IgE binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0389

F

From MGI

GO:0030246

carbohydrate binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001304

F

From MGI

GO:0046872

metal ion binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From MGI

GO:0051000

positive regulation of nitric-oxide synthase activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P06734

P

From MGI

GO:0051712

positive regulation of killing of cells of other organism

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P06734

P

From MGI

GO:0051770

positive regulation of nitric-oxide synthase biosynthetic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P06734

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Fujiwara H et al. (1994) The absence of IgE antibody-mediated augmentation of immune responses in CD23-deficient mice. Proc Natl Acad Sci U S A 91: 6835-9 PubMed GONUTS page
  2. Roes J & Rajewsky K (1993) Immunoglobulin D (IgD)-deficient mice reveal an auxiliary receptor function for IgD in antigen-mediated recruitment of B cells. J Exp Med 177: 45-55 PubMed GONUTS page
  3. Gerth AJ et al. (2003) T-bet regulates T-independent IgG2a class switching. Int Immunol 15: 937-44 PubMed GONUTS page
  4. Kretschmer K et al. (2003) The selection of marginal zone B cells differs from that of B-1a cells. J Immunol 171: 6495-501 PubMed GONUTS page
  5. Erlandsson L et al. (2005) Both the pre-BCR and the IL-7Ralpha are essential for expansion at the pre-BII cell stage in vivo. Eur J Immunol 35: 1969-76 PubMed GONUTS page
  6. Apasov SG et al. (2001) Adenosine deaminase deficiency increases thymic apoptosis and causes defective T cell receptor signaling. J Clin Invest 108: 131-41 PubMed GONUTS page
  7. Kong YY et al. (1995) Differential requirements of CD45 for lymphocyte development and function. Eur J Immunol 25: 3431-6 PubMed GONUTS page
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