Ambox notice.png

GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.

You can help reduce stress on the server by:

  1. not reloading pages frequently - this just adds
  2. opening links in new windows (so you can read the old page)

MGI:Fbxw11

From GONUTS
Jump to: navigation, search

Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Fbxw11 ( synonyms: BTRC2, BTRCP2, Fbxw1b, HOS )
Protein Name(s) F-box and WD-40 domain protein 11,
External Links
MGI MGI:2144023

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000209

protein polyubiquitination

MGI:MGI:2176150
PMID:11896578[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0000209

protein polyubiquitination

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UKB1

P

From MGI

GO:0004842

ubiquitin-protein ligase activity

MGI:MGI:2176150
PMID:11896578[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0004842

ubiquitin-protein ligase activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UKB1

F

From MGI

GO:0005515

protein binding

MGI:MGI:2176150
PMID:11896578[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q9WTX5
UniProtKB:Q9Z1E3

F

From MGI

GO:0005515

protein binding

MGI:MGI:4844267
PMID:18782782[2]

IPI: Inferred from Physical Interaction

UniProtKB:Q9Z301

F

From MGI

GO:0005634

nucleus

MGI:MGI:4844267
PMID:18782782[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:2176150
PMID:11896578[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005813

centrosome

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UKB1

C

From MGI

GO:0005829

cytosol

MGI:MGI:4844267
PMID:18782782[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0006470

protein dephosphorylation

MGI:MGI:4844267
PMID:18782782[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0007049

cell cycle

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0131

P

From MGI

GO:0016055

Wnt receptor signaling pathway

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0879

P

From MGI

GO:0016567

protein ubiquitination

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UKB1

P

From MGI

GO:0019005

SCF ubiquitin ligase complex

MGI:MGI:2176150
PMID:11896578[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0019005

SCF ubiquitin ligase complex

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UKB1

C

From MGI

GO:0031146

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

MGI:MGI:2176150
PMID:11896578[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0031146

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UKB1

P

From MGI

GO:0031648

protein destabilization

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UKB1

P

From MGI

GO:0042347

negative regulation of NF-kappaB import into nucleus

MGI:MGI:2176150
PMID:11896578[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0042753

positive regulation of circadian rhythm

MGI:MGI:4844267
PMID:18782782[2]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0043161

proteasomal ubiquitin-dependent protein catabolic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UKB1

P

From MGI

GO:0045862

positive regulation of proteolysis

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UKB1

P

From MGI

GO:0045892

negative regulation of transcription, DNA-dependent

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UKB1

P

From MGI

GO:0045893

positive regulation of transcription, DNA-dependent

MGI:MGI:4844267
PMID:18782782[2]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0046983

protein dimerization activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR021977

F

From MGI

GO:0048511

rhythmic process

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0090

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Bhatia N et al. (2002) Mouse homologue of HOS (mHOS) is overexpressed in skin tumors and implicated in constitutive activation of NF-kappaB. Oncogene 21: 1501-9 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 Ohsaki K et al. (2008) The role of {beta}-TrCP1 and {beta}-TrCP2 in circadian rhythm generation by mediating degradation of clock protein PER2. J Biochem 144: 609-18 PubMed GONUTS page
Personal tools
Namespaces
Variants
Actions
Navigation
Cacao
Journal Clubs
page contributors
Toolbox