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MGI:Fbl

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Fbl ( synonyms: RNU3IP1 )
Protein Name(s) fibrillarin,
External Links
MGI MGI:95486

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001651

dense fibrillar component

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P22509

C

From MGI

GO:0001652

granular component

MGI:MGI:3511413
PMID:15485902[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0003723

RNA binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P22509

F

From MGI

GO:0005634

nucleus

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From MGI

GO:0005730

nucleolus

MGI:MGI:2158991
PMID:11237729[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005730

nucleolus

MGI:MGI:2662932
PMID:12714744[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005730

nucleolus

MGI:MGI:3041997
PMID:14612397[4]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005730

nucleolus

MGI:MGI:3510094
PMID:15494374[5]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P22087

C

From MGI

GO:0005730

nucleolus

MGI:MGI:3689171
PMID:16855206[6]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005730

nucleolus

MGI:MGI:3696526
PMID:17158916[7]

ISO: Inferred from Sequence Orthology

UniProtKB:P22087

C

From MGI

GO:0005730

nucleolus

MGI:MGI:4462332
PMID:20168299[8]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005730

nucleolus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P22087

C

From MGI

GO:0005730

nucleolus

MGI:MGI:71480
PMID:7772340[9]

IDA: Inferred from Direct Assay

C

From MGI

GO:0006364

rRNA processing

MGI:MGI:63573
PMID:8218401[10]

TAS: Traceable Author Statement

P

From MGI

GO:0006396

RNA processing

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P22509

P

From MGI

GO:0008033

tRNA processing

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000692
InterPro:IPR020813

P

From MGI

GO:0008168

methyltransferase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0489

F

From MGI

GO:0008168

methyltransferase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000692
InterPro:IPR020813

F

From MGI

GO:0015030

Cajal body

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P22087

C

From MGI

GO:0015030

Cajal body

MGI:MGI:63573
PMID:8218401[10]

TAS: Traceable Author Statement

C

From MGI

GO:0015030

Cajal body

MGI:MGI:70929
PMID:7768196[11]

IDA: Inferred from Direct Assay

C

From MGI

GO:0016074

snoRNA metabolic process

MGI:MGI:3041997
PMID:14612397[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3043754

P

From MGI

GO:0016740

transferase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0808

F

From MGI

GO:0030515

snoRNA binding

MGI:MGI:63573
PMID:8218401[10]

TAS: Traceable Author Statement

F

From MGI

GO:0030529

ribonucleoprotein complex

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0687

C

From MGI

GO:0032259

methylation

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0489

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Brady SN et al. (2004) ARF impedes NPM/B23 shuttling in an Mdm2-sensitive tumor suppressor pathway. Mol Cell Biol 24: 9327-38 PubMed GONUTS page
  2. Fischer H et al. (2001) C7, a novel nucleolar protein, is the mouse homologue of the Drosophila late puff product L82 and an isoform of human OXR1. Biochem Biophys Res Commun 281: 795-803 PubMed GONUTS page
  3. Burns KH et al. (2003) Roles of NPM2 in chromatin and nucleolar organization in oocytes and embryos. Science 300: 633-6 PubMed GONUTS page
  4. 4.0 4.1 Newton K et al. (2003) Fibrillarin is essential for early development and required for accumulation of an intron-encoded small nucleolar RNA in the mouse. Mol Cell Biol 23: 8519-27 PubMed GONUTS page
  5. Yang Z et al. (2004) GW182 is critical for the stability of GW bodies expressed during the cell cycle and cell proliferation. J Cell Sci 117: 5567-78 PubMed GONUTS page
  6. Romanova LG et al. (2006) Implication of nucleolar protein SURF6 in ribosome biogenesis and preimplantation mouse development. Biol Reprod 75: 690-6 PubMed GONUTS page
  7. Meng L et al. (2006) Multiple controls regulate nucleostemin partitioning between nucleolus and nucleoplasm. J Cell Sci 119: 5124-36 PubMed GONUTS page
  8. Guetg C et al. (2010) The NoRC complex mediates the heterochromatin formation and stability of silent rRNA genes and centromeric repeats. EMBO J 29: 2135-46 PubMed GONUTS page
  9. Baran V et al. (1995) Localization of fibrillarin and nucleolin in nucleoli of mouse preimplantation embryos. Mol Reprod Dev 40: 305-10 PubMed GONUTS page
  10. 10.0 10.1 10.2 Turley SJ et al. (1993) Molecular cloning and sequence analysis of U3 snoRNA-associated mouse fibrillarin. Biochim Biophys Acta 1216: 119-22 PubMed GONUTS page
  11. Ferreira J & Carmo-Fonseca M (1995) The biogenesis of the coiled body during early mouse development. Development 121: 601-12 PubMed GONUTS page
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