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MGI:Fancc

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Fancc ( synonyms: Facc )
Protein Name(s) Fanconi anemia, complementation group C,
External Links
MGI MGI:95480

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000785

chromatin

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O35870

C

From MGI

GO:0002262

myeloid cell homeostasis

MGI:MGI:2149223
PMID:11493445[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:98351

P

From MGI

GO:0002262

myeloid cell homeostasis

MGI:MGI:2149223
PMID:11493445[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1858040

P

From MGI

GO:0005634

nucleus

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0963

C

From MGI

GO:0005829

cytosol

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q00597

C

From MGI

GO:0006281

DNA repair

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0234

P

From MGI

GO:0006281

DNA repair

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000686

P

From MGI

GO:0006289

nucleotide-excision repair

MGI:MGI:1355066
PMID:8704201[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1858041

P

From MGI

GO:0006974

response to DNA damage stimulus

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0227

P

From MGI

GO:0007276

gamete generation

MGI:MGI:79583
PMID:8630504[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1858040

P

From MGI

GO:0007281

germ cell development

MGI:MGI:1355066
PMID:8704201[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1858041

P

From MGI

GO:0019430

removal of superoxide radicals

MGI:MGI:2149223
PMID:11493445[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:98351

P

From MGI

GO:0043240

Fanconi anaemia nuclear complex

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q00597

C

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Hadjur S et al. (2001) Defective hematopoiesis and hepatic steatosis in mice with combined deficiencies of the genes encoding Fancc and Cu/Zn superoxide dismutase. Blood 98: 1003-11 PubMed GONUTS page
  2. 2.0 2.1 Whitney MA et al. (1996) Germ cell defects and hematopoietic hypersensitivity to gamma-interferon in mice with a targeted disruption of the Fanconi anemia C gene. Blood 88: 49-58 PubMed GONUTS page
  3. Chen M et al. (1996) Inactivation of Fac in mice produces inducible chromosomal instability and reduced fertility reminiscent of Fanconi anaemia. Nat Genet 12: 448-51 PubMed GONUTS page
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