GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
MGI:Fadd
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Fadd ( synonyms: Mort1/FADD ) | |
| Protein Name(s) | Fas (TNFRSF6)-associated via death domain, | |
| External Links | ||
| MGI | MGI:109324 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005164 |
tumor necrosis factor receptor binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_690920 |
F |
From MGI |
||
| GO:0005737 |
cytoplasm |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_690920 |
C |
From MGI |
||
| GO:0006915 |
apoptotic process |
MGI:MGI:2665373 |
RCA: Inferred from Reviewed Computational Analysis |
P |
From MGI |
|||
| GO:0006915 |
apoptotic process |
MGI:MGI:2675560 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0006915 |
apoptotic process |
MGI:MGI:3603971 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0007165 |
signal transduction |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0008624 |
induction of apoptosis by extracellular signals |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0031264 |
death-inducing signaling complex |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0031265 |
CD95 death-inducing signaling complex |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_690920 |
C |
From MGI |
||
| GO:0031265 |
CD95 death-inducing signaling complex |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0032757 |
positive regulation of interleukin-8 production |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0032760 |
positive regulation of tumor necrosis factor production |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0032813 |
tumor necrosis factor receptor superfamily binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0042802 |
identical protein binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0042981 |
regulation of apoptotic process |
MGI:MGI:2665373 |
RCA: Inferred from Reviewed Computational Analysis |
P |
From MGI |
|||
| GO:0042981 |
regulation of apoptotic process |
MGI:MGI:2675560 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0043005 |
neuron projection |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_690920 |
C |
From MGI |
||
| GO:0043065 |
positive regulation of apoptotic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0043234 |
protein complex |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_690920 |
C |
From MGI |
||
| GO:0044297 |
cell body |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_690920 |
C |
From MGI |
||
| GO:0045087 |
innate immune response |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0399 |
P |
From MGI |
||
| GO:0045121 |
membrane raft |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_690920 |
C |
From MGI |
||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0051291 |
protein heterooligomerization |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_690920 |
P |
From MGI |
||
| GO:0051607 |
defense response to virus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0060340 |
positive regulation of type I interferon-mediated signaling pathway |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0070265 |
necrotic cell death |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0097191 |
extrinsic apoptotic signaling pathway |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:2001238 |
positive regulation of extrinsic apoptotic signaling pathway |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Reed JC et al. (2003) Comparative analysis of apoptosis and inflammation genes of mice and humans. Genome Res 13: 1376-88 PubMed GONUTS page
- ↑ 2.0 2.1 Ugolini G et al. (2003) Fas/tumor necrosis factor receptor death signaling is required for axotomy-induced death of motoneurons in vivo. J Neurosci 23: 8526-31 PubMed GONUTS page
- ↑ Berube C et al. (2005) Apoptosis caused by p53-induced protein with death domain (PIDD) depends on the death adapter protein RAIDD. Proc Natl Acad Sci U S A 102: 14314-20 PubMed GONUTS page
