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MGI:Ext2
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Ext2 | |
| Protein Name(s) | exostoses (multiple) 2, | |
| External Links | ||
| MGI | MGI:108050 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000139 |
Golgi membrane |
MGI:MGI:3687782 |
IC: Inferred by Curator |
GO:0005794 |
C |
From MGI |
||
| GO:0001503 |
ossification |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0001707 |
mesoderm formation |
MGI:MGI:3608483 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3608690 |
P |
From MGI |
||
| GO:0005783 |
endoplasmic reticulum |
MGI:MGI:3687782 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005789 |
endoplasmic reticulum membrane |
MGI:MGI:3687782 |
IC: Inferred by Curator |
GO:0005783 |
C |
From MGI |
||
| GO:0005794 |
Golgi apparatus |
MGI:MGI:3687782 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0006024 |
glycosaminoglycan biosynthetic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0008152 |
metabolic process |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0808 |
P |
From MGI |
||
| GO:0008152 |
metabolic process |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0008152 |
metabolic process |
MGI:MGI:3687782 |
IC: Inferred by Curator |
GO:0008375 |
P |
From MGI |
||
| GO:0008152 |
metabolic process |
MGI:MGI:3687782 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0008375 |
acetylglucosaminyltransferase activity |
MGI:MGI:3687782 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0015012 |
heparan sulfate proteoglycan biosynthetic process |
MGI:MGI:3608483 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3608690 |
P |
From MGI |
||
| GO:0015012 |
heparan sulfate proteoglycan biosynthetic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0015014 |
heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0015020 |
glucuronosyltransferase activity |
MGI:MGI:3687782 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0015020 |
glucuronosyltransferase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016020 |
membrane |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0016021 |
integral to membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From MGI |
||
| GO:0016740 |
transferase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0808 |
F |
From MGI |
||
| GO:0016757 |
transferase activity, transferring glycosyl groups |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0016758 |
transferase activity, transferring hexosyl groups |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0030154 |
cell differentiation |
MGI:MGI:3608483 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3608690 |
P |
From MGI |
||
| GO:0031227 |
intrinsic to endoplasmic reticulum membrane |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0033692 |
cellular polysaccharide biosynthetic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0042328 |
heparan sulfate N-acetylglucosaminyltransferase activity |
MGI:MGI:3687782 |
IC: Inferred by Curator |
GO:0008375 |
F |
From MGI |
||
| GO:0042803 |
protein homodimerization activity |
MGI:MGI:3687782 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0046982 |
protein heterodimerization activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0050508 |
glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity |
MGI:MGI:3687782 |
IC: Inferred by Curator |
GO:0008375 |
F |
From MGI |
||
| GO:0050509 |
N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity |
MGI:MGI:3687782 |
IC: Inferred by Curator |
GO:0015020 |
F |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 McCormick C et al. (2000) The putative tumor suppressors EXT1 and EXT2 form a stable complex that accumulates in the Golgi apparatus and catalyzes the synthesis of heparan sulfate. Proc Natl Acad Sci U S A 97: 668-73 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Stickens D et al. (2005) Mice deficient in Ext2 lack heparan sulfate and develop exostoses. Development 132: 5055-68 PubMed GONUTS page
