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MGI:Exo1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Exo1 ( synonyms: Msa )
Protein Name(s) exonuclease 1,
External Links
MGI MGI:1349427

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0002455

humoral immune response mediated by circulating immunoglobulin

MGI:MGI:3028407
PMID:14716311[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2653925

P

From MGI

GO:0003677

DNA binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UQ84

F

From MGI

GO:0003824

catalytic activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR020045
InterPro:IPR008918

F

From MGI

GO:0004518

nuclease activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0267
UniProtKB-KW:KW-0540

F

From MGI

GO:0004518

nuclease activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR006086
InterPro:IPR006085
InterPro:IPR006084

F

From MGI

GO:0004519

endonuclease activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0255

F

From MGI

GO:0004527

exonuclease activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0269

F

From MGI

GO:0005634

nucleus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UQ84

C

From MGI

GO:0006139

nucleobase-containing compound metabolic process

MGI:MGI:1346707
PMID:10497278[2]

ISA: Inferred from Sequence Alignment

EMBL:AF042282

P

From MGI

GO:0006281

DNA repair

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0228
UniProtKB-KW:KW-0234

P

From MGI

GO:0006281

DNA repair

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR006086
InterPro:IPR006085
InterPro:IPR006084

P

From MGI

GO:0006298

mismatch repair

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UQ84

P

From MGI

GO:0006310

DNA recombination

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UQ84

P

From MGI

GO:0006974

response to DNA damage stimulus

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0227

P

From MGI

GO:0007126

meiosis

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0469

P

From MGI

GO:0008409

5'-3' exonuclease activity

MGI:MGI:1346707
PMID:10497278[2]

ISA: Inferred from Sequence Alignment

EMBL:AF042282

F

From MGI

GO:0016446

somatic hypermutation of immunoglobulin genes

MGI:MGI:3028407
PMID:14716311[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2653925

P

From MGI

GO:0016787

hydrolase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0378

F

From MGI

GO:0016788

hydrolase activity, acting on ester bonds

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR019974

F

From MGI

GO:0035312

5'-3' exodeoxyribonuclease activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UQ84

F

From MGI

GO:0043566

structure-specific DNA binding

MGI:MGI:3028407
PMID:14716311[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0045145

single-stranded DNA specific 5'-3' exodeoxyribonuclease activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UQ84

F

From MGI

GO:0045190

isotype switching

MGI:MGI:3028407
PMID:14716311[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2653925

P

From MGI

GO:0046872

metal ion binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From MGI

GO:0048256

flap endonuclease activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UQ84

F

From MGI

GO:0051908

double-stranded DNA specific 5'-3' exodeoxyribonuclease activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UQ84

F

From MGI

GO:0090305

nucleic acid phosphodiester bond hydrolysis

MGI:MGI:1346707
PMID:10497278[2]

ISA: Inferred from Sequence Alignment

EMBL:AF042282

P

From MGI

GO:0090305

nucleic acid phosphodiester bond hydrolysis

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0255

P

From MGI

GO:0090305

nucleic acid phosphodiester bond hydrolysis

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR006086
InterPro:IPR006085
InterPro:IPR006084

P

From MGI

GO:0090305

nucleic acid phosphodiester bond hydrolysis

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UQ84

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Bardwell PD et al. (2004) Altered somatic hypermutation and reduced class-switch recombination in exonuclease 1-mutant mice. Nat Immunol 5: 224-9 PubMed GONUTS page
  2. 2.0 2.1 2.2 Lee BI et al. (1999) Expression specificity of the mouse exonuclease 1 (mExo1) gene. Nucleic Acids Res 27: 4114-20 PubMed GONUTS page
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