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MGI:Espl1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Espl1 ( synonyms: Cerp, ESP1, PRCE, separase, SSE )
Protein Name(s) extra spindle poles-like 1 (S. cerevisiae),
External Links
MGI MGI:2146156

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000070

mitotic sister chromatid segregation

MGI:MGI:3622516
PMID:16533945[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3624200

P

From MGI

GO:0000070

mitotic sister chromatid segregation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q14674

P

From MGI

GO:0000090

mitotic anaphase

MGI:MGI:3622516
PMID:16533945[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3624200

P

From MGI

GO:0000212

meiotic spindle organization

MGI:MGI:2678956
PMID:14561405[2]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0005634

nucleus

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From MGI

GO:0005634

nucleus

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR005314

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0963

C

From MGI

GO:0005813

centrosome

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q14674

C

From MGI

GO:0006508

proteolysis

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0645

P

From MGI

GO:0006508

proteolysis

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR005314

P

From MGI

GO:0007059

chromosome segregation

MGI:MGI:3622516
PMID:16533945[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:1353578

P

From MGI

GO:0007127

meiosis I

MGI:MGI:2678956
PMID:14561405[2]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0008233

peptidase activity

MGI:MGI:4361070
PMID:19625504[3]

IDA: Inferred from Direct Assay

F

From MGI

GO:0008234

cysteine-type peptidase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0788

F

From MGI

GO:0016787

hydrolase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0378

F

From MGI

GO:0045143

homologous chromosome segregation

MGI:MGI:2678956
PMID:14561405[2]

IMP: Inferred from Mutant Phenotype

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Wirth KG et al. (2006) Separase: a universal trigger for sister chromatid disjunction but not chromosome cycle progression. J Cell Biol 172: 847-60 PubMed GONUTS page
  2. 2.0 2.1 2.2 Terret ME et al. (2003) The meiosis I-to-meiosis II transition in mouse oocytes requires separase activity. Curr Biol 13: 1797-802 PubMed GONUTS page
  3. Kudo NR et al. (2009) Role of cleavage by separase of the Rec8 kleisin subunit of cohesin during mammalian meiosis I. J Cell Sci 122: 2686-98 PubMed GONUTS page
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