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MGI:Eps15

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Eps15
Protein Name(s) epidermal growth factor receptor pathway substrate 15,
External Links
MGI MGI:104583

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004872

receptor activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0675

F

From MGI

GO:0005509

calcium ion binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011992
InterPro:IPR002048

F

From MGI

GO:0005515

protein binding

MGI:MGI:3687718
PMID:9446614[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q60902

F

From MGI

GO:0005515

protein binding

MGI:MGI:4821940
PMID:16771824[2]

IPI: Inferred from Physical Interaction

UniProtKB:Q80U87

F

From MGI

GO:0005515

protein binding

MGI:MGI:4887327
PMID:17626015[3]

IPI: Inferred from Physical Interaction

UniProtKB:Q8VD37

F

From MGI

GO:0005737

cytoplasm

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:B1AUU8

C

From MGI

GO:0005768

endosome

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0967

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P42566

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:4887327
PMID:17626015[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005905

coated pit

MGI:MGI:4830632
PMID:20427320[4]

IDA: Inferred from Direct Assay

C

From MGI

GO:0006810

transport

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0813

P

From MGI

GO:0015031

protein transport

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0653

P

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0017124

SH3 domain binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0729

F

From MGI

GO:0030122

AP-2 adaptor complex

MGI:MGI:4887327
PMID:17626015[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0030136

clathrin-coated vesicle

MGI:MGI:4887327
PMID:17626015[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0043231

intracellular membrane-bounded organelle

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:B1AUU8

C

From MGI

GO:0048268

clathrin coat assembly

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P42566

P

From MGI

GO:0060170

cilium membrane

MGI:MGI:4830632
PMID:20427320[4]

IDA: Inferred from Direct Assay

C

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Coda L et al. (1998) Eps15R is a tyrosine kinase substrate with characteristics of a docking protein possibly involved in coated pits-mediated internalization. J Biol Chem 273: 3003-12 PubMed GONUTS page
  2. Mizuno E et al. (2006) A deubiquitinating enzyme UBPY regulates the level of protein ubiquitination on endosomes. Traffic 7: 1017-31 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Uezu A et al. (2007) SGIP1alpha is an endocytic protein that directly interacts with phospholipids and Eps15. J Biol Chem 282: 26481-9 PubMed GONUTS page
  4. 4.0 4.1 Molla-Herman A et al. (2010) The ciliary pocket: an endocytic membrane domain at the base of primary and motile cilia. J Cell Sci 123: 1785-95 PubMed GONUTS page
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