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MGI:Epo

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Epo
Protein Name(s) erythropoietin,
External Links
MGI MGI:95407

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001525

angiogenesis

MGI:MGI:4943617
PMID:20299672[1]

TAS: Traceable Author Statement

P

From MGI

GO:0001666

response to hypoxia

MGI:MGI:3045517
PMID:15016652[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0003007

heart morphogenesis

MGI:MGI:4943617
PMID:20299672[1]

TAS: Traceable Author Statement

P

From MGI

GO:0005128

erythropoietin receptor binding

MGI:MGI:4943617
PMID:20299672[1]

TAS: Traceable Author Statement

F

From MGI

GO:0005179

hormone activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0372

F

From MGI

GO:0005179

hormone activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR019767
InterPro:IPR001323

F

From MGI

GO:0005576

extracellular region

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P29676

C

From MGI

GO:0005615

extracellular space

MGI:MGI:3045517
PMID:15016652[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005615

extracellular space

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P29676

C

From MGI

GO:0005615

extracellular space

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01588

C

From MGI

GO:0006357

regulation of transcription from RNA polymerase II promoter

MGI:MGI:3762687
PMID:17300687[3]

IDA: Inferred from Direct Assay

P

From MGI

GO:0006915

apoptotic process

MGI:MGI:3762687
PMID:17300687[3]

IDA: Inferred from Direct Assay

P

From MGI

GO:0006916

anti-apoptosis

MGI:MGI:5009772
PMID:21095239[4]

IDA: Inferred from Direct Assay

P

From MGI

GO:0007566

embryo implantation

MGI:MGI:3762687
PMID:17300687[3]

IDA: Inferred from Direct Assay

P

From MGI

GO:0008284

positive regulation of cell proliferation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01588

P

From MGI

GO:0010766

negative regulation of sodium ion transport

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01588

P

From MGI

GO:0018105

peptidyl-serine phosphorylation

MGI:MGI:5009772
PMID:21095239[4]

IDA: Inferred from Direct Assay

P

From MGI

GO:0030218

erythrocyte differentiation

MGI:MGI:3578483
PMID:15591122[5]

IDA: Inferred from Direct Assay

P

From MGI

GO:0030295

protein kinase activator activity

MGI:MGI:5009772
PMID:21095239[4]

IDA: Inferred from Direct Assay

F

From MGI

GO:0032413

negative regulation of ion transmembrane transporter activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01588

P

From MGI

GO:0042523

positive regulation of tyrosine phosphorylation of Stat5 protein

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01588

P

From MGI

GO:0042541

hemoglobin biosynthetic process

MGI:MGI:3762687
PMID:17300687[3]

IDA: Inferred from Direct Assay

P

From MGI

GO:0043066

negative regulation of apoptotic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01588

P

From MGI

GO:0043249

erythrocyte maturation

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0265

P

From MGI

GO:0043499

eukaryotic cell surface binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01588

F

From MGI

GO:0043526

neuroprotection

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P29676

P

From MGI

GO:0045666

positive regulation of neuron differentiation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P29676

P

From MGI

GO:0045740

positive regulation of DNA replication

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01588

P

From MGI

GO:0045860

positive regulation of protein kinase activity

MGI:MGI:5009772
PMID:21095239[4]

IDA: Inferred from Direct Assay

P

From MGI

GO:0045893

positive regulation of transcription, DNA-dependent

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01588

P

From MGI

GO:0046579

positive regulation of Ras protein signal transduction

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01588

P

From MGI

GO:0055008

cardiac muscle tissue morphogenesis

MGI:MGI:4943617
PMID:20299672[1]

TAS: Traceable Author Statement

P

From MGI

GO:0055010

ventricular cardiac muscle tissue morphogenesis

MGI:MGI:4943617
PMID:20299672[1]

TAS: Traceable Author Statement

P

From MGI

GO:0060979

vasculogenesis involved in coronary vascular morphogenesis

MGI:MGI:4943617
PMID:20299672[1]

TAS: Traceable Author Statement

P

From MGI

GO:0061032

visceral serous pericardium development

MGI:MGI:4943617
PMID:20299672[1]

TAS: Traceable Author Statement

P

From MGI

GO:0071474

cellular hyperosmotic response

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01588

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Olivey HE & Svensson EC (2010) Epicardial-myocardial signaling directing coronary vasculogenesis. Circ Res 106: 818-32 PubMed GONUTS page
  2. 2.0 2.1 Suliman HB et al. (2004) Superoxide dismutase-3 promotes full expression of the EPO response to hypoxia. Blood 104: 43-50 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Yasuda Y et al. (2007) Erythropoietin contributes to implantation: ectopic hemoglobin synthesis in decidual cells of mice. Congenit Anom (Kyoto) 47: 22-33 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 Deng H et al. (2011) Phosphorylation of Bcl-associated death protein (Bad) by erythropoietin-activated c-Jun N-terminal protein kinase 1 contributes to survival of erythropoietin-dependent cells. Int J Biochem Cell Biol 43: 409-15 PubMed GONUTS page
  5. Lenox LE et al. (2005) BMP4 and Madh5 regulate the erythroid response to acute anemia. Blood 105: 2741-8 PubMed GONUTS page
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