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MGI:Epm2a
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Epm2a ( synonyms: laforin ) | |
| Protein Name(s) | epilepsy, progressive myoclonic epilepsy, type 2 gene alpha, | |
| External Links | ||
| MGI | MGI:1341085 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004722 |
protein serine/threonine phosphatase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0004725 |
protein tyrosine phosphatase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3758968 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:3758968 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005829 |
cytosol |
MGI:MGI:2675701 |
ISA: Inferred from Sequence Alignment |
C |
From MGI |
|||
| GO:0005829 |
cytosol |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005844 |
polysome |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006470 |
protein dephosphorylation |
MGI:MGI:4459044 |
PANTHER:PTHR10159 |
P |
From MGI |
|||
| GO:0006470 |
protein dephosphorylation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0007399 |
nervous system development |
MGI:MGI:2179940 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2182627 |
P |
From MGI |
||
| GO:0007610 |
behavior |
MGI:MGI:2179940 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2182627 |
P |
From MGI |
||
| GO:0008138 |
protein tyrosine/serine/threonine phosphatase activity |
MGI:MGI:2179940 |
TAS: Traceable Author Statement |
F |
From MGI |
|||
| GO:0008138 |
protein tyrosine/serine/threonine phosphatase activity |
MGI:MGI:4459044 |
PANTHER:PTHR10159 |
F |
From MGI |
|||
| GO:0016787 |
hydrolase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0378 |
F |
From MGI |
||
| GO:0035335 |
peptidyl-tyrosine dephosphorylation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Cheng A et al. (2007) A role for AGL ubiquitination in the glycogen storage disorders of Lafora and Cori's disease. Genes Dev 21: 2399-409 PubMed GONUTS page
- ↑ Ganesh S et al. (2003) The Lafora disease gene product laforin interacts with HIRIP5, a phylogenetically conserved protein containing a NifU-like domain. Hum Mol Genet 12: 2359-68 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Ganesh S et al. (2002) Targeted disruption of the Epm2a gene causes formation of Lafora inclusion bodies, neurodegeneration, ataxia, myoclonus epilepsy and impaired behavioral response in mice. Hum Mol Genet 11: 1251-62 PubMed GONUTS page
