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MGI:Enah
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Enah ( synonyms: Mena, Ndpp1 ) | |
| Protein Name(s) | enabled homolog (Drosophila), | |
| External Links | ||
| MGI | MGI:108360 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001725 |
stress fiber |
MGI:MGI:1099567 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0001843 |
neural tube closure |
MGI:MGI:1331576 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:97549 |
P |
From MGI |
||
| GO:0001843 |
neural tube closure |
MGI:MGI:3054149 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:109268 |
P |
From MGI |
||
| GO:0003779 |
actin binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0009 |
F |
From MGI |
||
| GO:0005515 |
protein binding |
MGI:MGI:1099567 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:2664008 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3046012 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005522 |
profilin binding |
MGI:MGI:1331576 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005625 |
soluble fraction |
MGI:MGI:3846509 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005856 |
cytoskeleton |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0206 |
C |
From MGI |
||
| GO:0005886 |
plasma membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005925 |
focal adhesion |
MGI:MGI:1099567 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005925 |
focal adhesion |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006928 |
cellular component movement |
MGI:MGI:1099567 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0007015 |
actin filament organization |
MGI:MGI:1099567 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0007275 |
multicellular organismal development |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0217 |
P |
From MGI |
||
| GO:0007399 |
nervous system development |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0524 |
P |
From MGI |
||
| GO:0007411 |
axon guidance |
MGI:MGI:1331576 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3056050 |
P |
From MGI |
||
| GO:0007411 |
axon guidance |
MGI:MGI:3054149 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:109268 |
P |
From MGI |
||
| GO:0007411 |
axon guidance |
MGI:MGI:3054149 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3056050 |
P |
From MGI |
||
| GO:0008154 |
actin polymerization or depolymerization |
MGI:MGI:1099567 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0015629 |
actin cytoskeleton |
MGI:MGI:1331576 |
TAS: Traceable Author Statement |
C |
From MGI |
|||
| GO:0017124 |
SH3 domain binding |
MGI:MGI:1326779 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0030027 |
lamellipodium |
MGI:MGI:2664008 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0030027 |
lamellipodium |
MGI:MGI:3046012 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0030036 |
actin cytoskeleton organization |
MGI:MGI:3054149 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:109268 |
P |
From MGI |
||
| GO:0030054 |
cell junction |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0030154 |
cell differentiation |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0221 |
P |
From MGI |
||
| GO:0030175 |
filopodium |
MGI:MGI:1331576 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0030175 |
filopodium |
MGI:MGI:3046012 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0042995 |
cell projection |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0966 |
C |
From MGI |
||
| GO:0045202 |
synapse |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0770 |
C |
From MGI |
||
| GO:0046907 |
intracellular transport |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0050699 |
WW domain binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Gertler FB et al. (1996) Mena, a relative of VASP and Drosophila Enabled, is implicated in the control of microfilament dynamics. Cell 87: 227-39 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Lanier LM et al. (1999) Mena is required for neurulation and commissure formation. Neuron 22: 313-25 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Menzies AS et al. (2004) Mena and vasodilator-stimulated phosphoprotein are required for multiple actin-dependent processes that shape the vertebrate nervous system. J Neurosci 24: 8029-38 PubMed GONUTS page
- ↑ 4.0 4.1 Tani K et al. (2003) Abl interactor 1 promotes tyrosine 296 phosphorylation of mammalian enabled (Mena) by c-Abl kinase. J Biol Chem 278: 21685-92 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 Tanoue T & Takeichi M (2004) Mammalian Fat1 cadherin regulates actin dynamics and cell-cell contact. J Cell Biol 165: 517-28 PubMed GONUTS page
- ↑ Sawallisch C et al. (2009) The insulin receptor substrate of 53 kDa (IRSp53) limits hippocampal synaptic plasticity. J Biol Chem 284: 9225-36 PubMed GONUTS page
- ↑ Yamabhai M & Kay BK (1997) Examining the specificity of Src homology 3 domain--ligand interactions with alkaline phosphatase fusion proteins. Anal Biochem 247: 143-51 PubMed GONUTS page
