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MGI:En1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | En1 ( synonyms: En-1, engrailed-1, Mo-en.1 ) | |
| Protein Name(s) | engrailed 1, | |
| External Links | ||
| MGI | MGI:95389 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003677 |
DNA binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0238 |
F |
From MGI |
||
| GO:0003677 |
DNA binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005624 |
membrane fraction |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:XP_001056699 |
C |
From MGI |
||
| GO:0005634 |
nucleus |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:XP_001056699 |
C |
From MGI |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007275 |
multicellular organismal development |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0217 |
P |
From MGI |
||
| GO:0007275 |
multicellular organismal development |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0009953 |
dorsal/ventral pattern formation |
MGI:MGI:1194987 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857163 |
P |
From MGI |
||
| GO:0009953 |
dorsal/ventral pattern formation |
MGI:MGI:81767 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857163 |
P |
From MGI |
||
| GO:0009954 |
proximal/distal pattern formation |
MGI:MGI:1194987 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857163 |
P |
From MGI |
||
| GO:0009954 |
proximal/distal pattern formation |
MGI:MGI:81767 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857163 |
P |
From MGI |
||
| GO:0030182 |
neuron differentiation |
MGI:MGI:3522127 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:95390 |
P |
From MGI |
||
| GO:0030182 |
neuron differentiation |
MGI:MGI:3525936 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:95390 |
P |
From MGI |
||
| GO:0030182 |
neuron differentiation |
MGI:MGI:3578062 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:95390 |
P |
From MGI |
||
| GO:0030326 |
embryonic limb morphogenesis |
MGI:MGI:3052394 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:2384508 |
P |
From MGI |
||
| GO:0030326 |
embryonic limb morphogenesis |
MGI:MGI:81767 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857163 |
P |
From MGI |
||
| GO:0030901 |
midbrain development |
MGI:MGI:3525936 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:95390 |
P |
From MGI |
||
| GO:0030901 |
midbrain development |
MGI:MGI:3578062 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:95390 |
P |
From MGI |
||
| GO:0030902 |
hindbrain development |
MGI:MGI:3525936 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:95390 |
P |
From MGI |
||
| GO:0030917 |
midbrain-hindbrain boundary development |
MGI:MGI:3525936 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857163 |
P |
From MGI |
||
| GO:0035115 |
embryonic forelimb morphogenesis |
MGI:MGI:1194987 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:98961 |
P |
From MGI |
||
| GO:0043473 |
pigmentation |
MGI:MGI:1194987 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857163 |
P |
From MGI |
||
| GO:0043565 |
sequence-specific DNA binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
MGI:MGI:86732 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0048666 |
neuron development |
MGI:MGI:1933708 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:95390 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Cygan JA et al. (1997) Novel regulatory interactions revealed by studies of murine limb pattern in Wnt-7a and En-1 mutants. Development 124: 5021-32 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Loomis CA et al. (1996) The mouse Engrailed-1 gene and ventral limb patterning. Nature 382: 360-3 PubMed GONUTS page
- ↑ Simon HH et al. (2004) Midbrain dopaminergic neurons: control of their cell fate by the engrailed transcription factors. Cell Tissue Res 318: 53-61 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 Simon HH et al. (2005) Engrailed genes control developmental fate of serotonergic and noradrenergic neurons in mid- and hindbrain in a gene dose-dependent manner. Mol Cell Neurosci 28: 96-105 PubMed GONUTS page
- ↑ 5.0 5.1 Albéri L et al. (2004) Engrailed genes are cell-autonomously required to prevent apoptosis in mesencephalic dopaminergic neurons. Development 131: 3229-36 PubMed GONUTS page
- ↑ Adamska M et al. (2004) En1 and Wnt7a interact with Dkk1 during limb development in the mouse. Dev Biol 272: 134-44 PubMed GONUTS page
- ↑ Küry P et al. (1997) Protease nexin-1 is expressed at the mouse met-/mesencephalic junction and FGF signaling regulates its promoter activity in primary met-/mesencephalic cells. Development 124: 1251-62 PubMed GONUTS page
- ↑ Simon HH et al. (2001) Fate of midbrain dopaminergic neurons controlled by the engrailed genes. J Neurosci 21: 3126-34 PubMed GONUTS page
