GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
MGI:Emx2
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Emx2 ( synonyms: Pdo ) | |
| Protein Name(s) | empty spiracles homolog 2 (Drosophila), | |
| External Links | ||
| MGI | MGI:95388 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003677 |
DNA binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0238 |
F |
From MGI |
||
| GO:0005634 |
nucleus |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0539 |
C |
From MGI |
||
| GO:0007420 |
brain development |
MGI:MGI:2181082 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2136350 |
P |
From MGI |
||
| GO:0007420 |
brain development |
MGI:MGI:2385980 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2148858 |
P |
From MGI |
||
| GO:0007420 |
brain development |
MGI:MGI:2386059 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2148858 |
P |
From MGI |
||
| GO:0007420 |
brain development |
MGI:MGI:2451205 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2148858 |
P |
From MGI |
||
| GO:0009952 |
anterior/posterior pattern specification |
MGI:MGI:2386059 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2148858 |
P |
From MGI |
||
| GO:0009952 |
anterior/posterior pattern specification |
MGI:MGI:3578670 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:97490 |
P |
From MGI |
||
| GO:0010468 |
regulation of gene expression |
MGI:MGI:3606726 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2148858 |
P |
From MGI |
||
| GO:0010468 |
regulation of gene expression |
MGI:MGI:3694536 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0021542 |
dentate gyrus development |
MGI:MGI:2153372 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2148858 |
P |
From MGI |
||
| GO:0021796 |
cerebral cortex regionalization |
MGI:MGI:3043493 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:95387 |
P |
From MGI |
||
| GO:0021796 |
cerebral cortex regionalization |
MGI:MGI:3606726 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2148858 |
P |
From MGI |
||
| GO:0021846 |
cell proliferation in forebrain |
MGI:MGI:2153372 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2148858 |
P |
From MGI |
||
| GO:0021885 |
forebrain cell migration |
MGI:MGI:2153372 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2148858 |
P |
From MGI |
||
| GO:0021987 |
cerebral cortex development |
MGI:MGI:3606726 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:95387 |
P |
From MGI |
||
| GO:0030182 |
neuron differentiation |
MGI:MGI:2451205 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2148858 |
P |
From MGI |
||
| GO:0030900 |
forebrain development |
MGI:MGI:3531270 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2148858 |
P |
From MGI |
||
| GO:0030900 |
forebrain development |
MGI:MGI:3578670 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:97451 |
P |
From MGI |
||
| GO:0042493 |
response to drug |
MGI:MGI:87440 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0072001 |
renal system development |
MGI:MGI:5085923 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:97486 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Shinozaki K et al. (2002) Absence of Cajal-Retzius cells and subplate neurons associated with defects of tangential cell migration from ganglionic eminence in Emx1/2 double mutant cerebral cortex. Development 129: 3479-92 PubMed GONUTS page
- ↑ López-Bendito G et al. (2002) Role of Emx2 in the development of the reciprocal connectivity between cortex and thalamus. J Comp Neurol 451: 153-69 PubMed GONUTS page
- ↑ 3.0 3.1 Bishop KM et al. (2002) Distinct actions of Emx1, Emx2, and Pax6 in regulating the specification of areas in the developing neocortex. J Neurosci 22: 7627-38 PubMed GONUTS page
- ↑ 4.0 4.1 Bishop KM et al. (2003) Emx1 and Emx2 cooperate to regulate cortical size, lamination, neuronal differentiation, development of cortical efferents, and thalamocortical pathfinding. J Comp Neurol 457: 345-60 PubMed GONUTS page
- ↑ 5.0 5.1 Kimura J et al. (2005) Emx2 and Pax6 function in cooperation with Otx2 and Otx1 to develop caudal forebrain primordium that includes future archipallium. J Neurosci 25: 5097-108 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 Muzio L & Mallamaci A (2003) Emx1, emx2 and pax6 in specification, regionalization and arealization of the cerebral cortex. Cereb Cortex 13: 641-7 PubMed GONUTS page
- ↑ Li H et al. (2006) Potential target genes of EMX2 include Odz/Ten-M and other gene families with implications for cortical patterning. Mol Cell Neurosci 33: 136-49 PubMed GONUTS page
- ↑ 8.0 8.1 8.2 Tole S et al. (2000) Emx2 is required for growth of the hippocampus but not for hippocampal field specification. J Neurosci 20: 2618-25 PubMed GONUTS page
- ↑ Shinozaki K et al. (2004) Emx1 and Emx2 cooperate in initial phase of archipallium development. Mech Dev 121: 475-89 PubMed GONUTS page
- ↑ Hamasaki T et al. (2004) EMX2 regulates sizes and positioning of the primary sensory and motor areas in neocortex by direct specification of cortical progenitors. Neuron 43: 359-72 PubMed GONUTS page
- ↑ Wlodarczyk BC et al. (1996) Valproic acid-induced changes in gene expression during neurulation in a mouse model. Teratology 54: 284-97 PubMed GONUTS page
- ↑ Boualia SK et al. (2011) Vesicoureteral reflux and other urinary tract malformations in mice compound heterozygous for Pax2 and Emx2. PLoS One 6: e21529 PubMed GONUTS page
abc |
dfn |
n cont.r |
