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MGI:Ela2

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Mus musculus (house mouse)

Ela2:elastase 2, neutrophil
Synonyms:NE
Ela2 on MGI

GO terms

GO:0004252_!_serine-type_endopeptidase_activity (F) IEA with/from InterPro:IPR018114,InterPro:IPR001254,InterPro:IPR001314 [1]
GO:0005515_!_protein_binding (F) ISO with/from UniProtKB:B2MUD5 [2]
GO:0006508_!_proteolysis (P) IEA with/from InterPro:IPR018114,InterPro:IPR001254,InterPro:IPR001314 [1]
GO:0006909_!_phagocytosis (P) IMP with/from MGI:MGI:2182771 [3]
GO:0008233_!_peptidase_activity (F) IEA with/from SP_KW:KW-0645 [4]
GO:0008236_!_serine-type_peptidase_activity (F) IEA with/from SP_KW:KW-0720 [4]
GO:0016787_!_hydrolase_activity (F) IEA with/from SP_KW:KW-0378 [4]
GO:0050900_!_leukocyte_migration (P) IMP with/from MGI:MGI:2182771 [3]
GO:0051603_!_proteolysis_involved_in_cellular_protein_catabolic_process (P) ISO with/from UniProtKB:B2MUD5 [2]

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Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 MGI annotation MGI:2152098
  2. 2.0 2.1 Barbour KW et al. (2002) Functional diversification during evolution of the murine alpha(1)-proteinase inhibitor family: role of the hypervariable reactive center loop. Mol Biol Evol 19: 718-27 PubMed GONUTS page
  3. 3.0 3.1 Young RE et al. (2004) Neutrophil elastase (NE)-deficient mice demonstrate a nonredundant role for NE in neutrophil migration, generation of proinflammatory mediators, and phagocytosis in response to zymosan particles in vivo. J Immunol 172: 4493-502 PubMed GONUTS page
  4. 4.0 4.1 4.2 MGI annotation MGI:1354194
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