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MGI:Eif4e

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Eif4e ( synonyms: eIF-4E, If4e )
Protein Name(s) eukaryotic translation initiation factor 4E,
External Links
MGI MGI:95305

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000082

G1/S transition of mitotic cell cycle

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P06730

P

From MGI

GO:0000932

cytoplasmic mRNA processing body

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:P06730

C

From MGI

GO:0003723

RNA binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0694

F

From MGI

GO:0003723

RNA binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001040
InterPro:IPR019770

F

From MGI

GO:0003743

translation initiation factor activity

MGI:MGI:3690190
PMID:16289705[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005515

protein binding

MGI:MGI:3700413
PMID:11500381[2]

IPI: Inferred from Physical Interaction

UniProtKB:P29590-4

F

From MGI

GO:0005515

protein binding

MGI:MGI:4418608
PMID:18805096[3]

IPI: Inferred from Physical Interaction

UniProtKB:Q7TMB8

F

From MGI

GO:0005737

cytoplasm

MGI:MGI:2450792
PMID:12388085[4]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005845

mRNA cap binding complex

MGI:MGI:4418608
PMID:18805096[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005845

mRNA cap binding complex

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P06730

C

From MGI

GO:0006412

translation

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0648

P

From MGI

GO:0006417

regulation of translation

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0810

P

From MGI

GO:0016281

eukaryotic translation initiation factor 4F complex

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P63074

C

From MGI

GO:0016442

RNA-induced silencing complex

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:P06730

C

From MGI

GO:0031370

eukaryotic initiation factor 4G binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P63074

F

From MGI

GO:0043234

protein complex

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P63074

C

From MGI

GO:0045931

positive regulation of mitotic cell cycle

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P06730

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Mikami S et al. (2006) An efficient mammalian cell-free translation system supplemented with translation factors. Protein Expr Purif 46: 348-57 PubMed GONUTS page
  2. Cohen N et al. (2001) PML RING suppresses oncogenic transformation by reducing the affinity of eIF4E for mRNA. EMBO J 20: 4547-59 PubMed GONUTS page
  3. 3.0 3.1 Napoli I et al. (2008) The fragile X syndrome protein represses activity-dependent translation through CYFIP1, a new 4E-BP. Cell 134: 1042-54 PubMed GONUTS page
  4. Kimball SR et al. (2003) Mammalian stress granules represent sites of accumulation of stalled translation initiation complexes. Am J Physiol Cell Physiol 284: C273-84 PubMed GONUTS page
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