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MGI:Ehhadh

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Ehhadh ( synonyms: HD, L-bifunctional enzyme, L-PBE, MFP, MFP1 )
Protein Name(s) enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase,
External Links
MGI MGI:1277964

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR016040

F

From MGI

GO:0003824

catalytic activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0511

F

From MGI

GO:0003824

catalytic activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001753
InterPro:IPR018376

F

From MGI

GO:0003857

3-hydroxyacyl-CoA dehydrogenase activity

MGI:MGI:1337902
PMID:10336479[1]

TAS: Traceable Author Statement

F

From MGI

GO:0003857

3-hydroxyacyl-CoA dehydrogenase activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P07896

F

From MGI

GO:0004165

dodecenoyl-CoA delta-isomerase activity

MGI:MGI:2152096

IEA: Inferred from Electronic Annotation

EC:5.3.3.8

F

From MGI

GO:0004300

enoyl-CoA hydratase activity

MGI:MGI:2152096

IEA: Inferred from Electronic Annotation

EC:4.2.1.17

F

From MGI

GO:0005634

nucleus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:F5GWL9

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:F5GWL9

C

From MGI

GO:0005739

mitochondrion

MGI:MGI:2682130
PMID:14651853[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005739

mitochondrion

MGI:MGI:3852644
PMID:18614015[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005777

peroxisome

MGI:MGI:1337902
PMID:10336479[1]

TAS: Traceable Author Statement

C

From MGI

GO:0005777

peroxisome

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P07896

C

From MGI

GO:0005777

peroxisome

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q08426

C

From MGI

GO:0006475

internal protein amino acid acetylation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q08426

P

From MGI

GO:0006629

lipid metabolic process

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0443

P

From MGI

GO:0006631

fatty acid metabolic process

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0276

P

From MGI

GO:0006631

fatty acid metabolic process

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR006180
InterPro:IPR006176
InterPro:IPR006108

P

From MGI

GO:0006635

fatty acid beta-oxidation

MGI:MGI:1337902
PMID:10336479[1]

TAS: Traceable Author Statement

P

From MGI

GO:0006635

fatty acid beta-oxidation

MGI:MGI:3711634
PMID:17442273[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857810

P

From MGI

GO:0006637

acyl-CoA metabolic process

MGI:MGI:1337902
PMID:10336479[1]

TAS: Traceable Author Statement

P

From MGI

GO:0008152

metabolic process

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0511

P

From MGI

GO:0008152

metabolic process

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001753
InterPro:IPR018376

P

From MGI

GO:0016491

oxidoreductase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0560

F

From MGI

GO:0016491

oxidoreductase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR006180
InterPro:IPR006176
InterPro:IPR006108
InterPro:IPR013328

F

From MGI

GO:0016616

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR013328

F

From MGI

GO:0016829

lyase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0456

F

From MGI

GO:0016853

isomerase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0413

F

From MGI

GO:0043231

intracellular membrane-bounded organelle

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:F5GWL9

C

From MGI

GO:0050662

coenzyme binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR013328

F

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Qi C et al. (1999) Absence of spontaneous peroxisome proliferation in enoyl-CoA Hydratase/L-3-hydroxyacyl-CoA dehydrogenase-deficient mouse liver. Further support for the role of fatty acyl CoA oxidase in PPARalpha ligand metabolism. J Biol Chem 274: 15775-80 PubMed GONUTS page
  2. Mootha VK et al. (2003) Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Cell 115: 629-40 PubMed GONUTS page
  3. Pagliarini DJ et al. (2008) A mitochondrial protein compendium elucidates complex I disease biology. Cell 134: 112-23 PubMed GONUTS page
  4. Dirkx R et al. (2007) Beta-oxidation in hepatocyte cultures from mice with peroxisomal gene knockouts. Biochem Biophys Res Commun 357: 718-23 PubMed GONUTS page
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