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MGI:Efnb2

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Efnb2 ( synonyms: ELF-2, Epl5, Eplg5, Htk-L, LERK-5, Lerk5, NLERK-1 )
Protein Name(s) ephrin B2,
External Links
MGI MGI:105097

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001525

angiogenesis

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0037

P

From MGI

GO:0001945

lymph vessel development

MGI:MGI:3527923
PMID:15687262[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3573787

P

From MGI

GO:0002042

cell migration involved in sprouting angiogenesis

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P52799

P

From MGI

GO:0005102

receptor binding

MGI:MGI:2155002
PMID:11780069[2]

IPI: Inferred from Physical Interaction

UniProtKB:P54763

F

From MGI

GO:0005515

protein binding

MGI:MGI:3810017
PMID:18555774[3]

IPI: Inferred from Physical Interaction

UniProtKB:Q03137

F

From MGI

GO:0005886

plasma membrane

MGI:MGI:3047196
PMID:15223334[4]

IDA: Inferred from Direct Assay

C

From MGI

GO:0007155

cell adhesion

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P52799

P

From MGI

GO:0007219

Notch signaling pathway

MGI:MGI:3701380
PMID:17336907[5]

IDA: Inferred from Direct Assay

P

From MGI

GO:0007275

multicellular organismal development

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0217

P

From MGI

GO:0007399

nervous system development

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0524

P

From MGI

GO:0009887

organ morphogenesis

MGI:MGI:3047196
PMID:15223334[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3051215
MGI:MGI:3051214

P

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016020

membrane

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001799
InterPro:IPR019765

C

From MGI

GO:0016021

integral to membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0812

C

From MGI

GO:0030154

cell differentiation

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0221

P

From MGI

GO:0046875

ephrin receptor binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P52799

F

From MGI

GO:0048013

ephrin receptor signaling pathway

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P52799

P

From MGI

GO:0050920

regulation of chemotaxis

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P52799

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Mäkinen T et al. (2005) PDZ interaction site in ephrinB2 is required for the remodeling of lymphatic vasculature. Genes Dev 19: 397-410 PubMed GONUTS page
  2. Himanen JP et al. (2001) Crystal structure of an Eph receptor-ephrin complex. Nature 414: 933-8 PubMed GONUTS page
  3. Tsuda H et al. (2008) The amyotrophic lateral sclerosis 8 protein VAPB is cleaved, secreted, and acts as a ligand for Eph receptors. Cell 133: 963-77 PubMed GONUTS page
  4. 4.0 4.1 Dravis C et al. (2004) Bidirectional signaling mediated by ephrin-B2 and EphB2 controls urorectal development. Dev Biol 271: 272-90 PubMed GONUTS page
  5. Grego-Bessa J et al. (2007) Notch signaling is essential for ventricular chamber development. Dev Cell 12: 415-29 PubMed GONUTS page
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