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MGI:Edn3

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Edn3 ( synonyms: 114-CH19, 114CH19, tmgc48 )
Protein Name(s) endothelin 3,
External Links
MGI MGI:95285

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001755

neural crest cell migration

MGI:MGI:1267304
PMID:9624616[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1856392

P

From MGI

GO:0002690

positive regulation of leukocyte chemotaxis

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P14138

P

From MGI

GO:0003100

regulation of systemic arterial blood pressure by endothelin

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P14138

P

From MGI

GO:0005179

hormone activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P14138

F

From MGI

GO:0005576

extracellular region

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0964

C

From MGI

GO:0005576

extracellular region

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR019764
InterPro:IPR001928

C

From MGI

GO:0005615

extracellular space

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P14138

C

From MGI

GO:0005622

intracellular

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P14138

C

From MGI

GO:0005623

cell

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P14138

C

From MGI

GO:0007166

cell surface receptor signaling pathway

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P14138

P

From MGI

GO:0008284

positive regulation of cell proliferation

MGI:MGI:1934508
PMID:11401406[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0010460

positive regulation of heart rate

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P14138

P

From MGI

GO:0014826

vein smooth muscle contraction

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P14138

P

From MGI

GO:0019229

regulation of vasoconstriction

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR019764
InterPro:IPR001928

P

From MGI

GO:0030072

peptide hormone secretion

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P14138

P

From MGI

GO:0030182

neuron differentiation

MGI:MGI:1267304
PMID:9624616[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1856392

P

From MGI

GO:0030318

melanocyte differentiation

MGI:MGI:85072
PMID:9012511[3]

IDA: Inferred from Direct Assay

P

From MGI

GO:0030334

regulation of cell migration

MGI:MGI:60945
PMID:14138974[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1856392

P

From MGI

GO:0030593

neutrophil chemotaxis

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P14138

P

From MGI

GO:0042310

vasoconstriction

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P14138

P

From MGI

GO:0043406

positive regulation of MAP kinase activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P14138

P

From MGI

GO:0045840

positive regulation of mitosis

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P14138

P

From MGI

GO:0046887

positive regulation of hormone secretion

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P14138

P

From MGI

GO:0046888

negative regulation of hormone secretion

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P13207

P

From MGI

GO:0046928

regulation of neurotransmitter secretion

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P13207

P

From MGI

GO:0048016

inositol phosphate-mediated signaling

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P14138

P

From MGI

GO:0048070

regulation of developmental pigmentation

MGI:MGI:60945
PMID:14138974[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1856392

P

From MGI

GO:0050880

regulation of blood vessel size

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0838

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Howard MJ & Gershon MD (1998) Development of LBP110 expression by neural crest-derived enteric precursors: migration and differentiation potential in ls/ls mutant mice. J Neurobiol 35: 341-54 PubMed GONUTS page
  2. Wehrle-Haller B et al. (2001) Analysis of melanocyte precursors in Nf1 mutants reveals that MGF/KIT signaling promotes directed cell migration independent of its function in cell survival. Dev Biol 232: 471-83 PubMed GONUTS page
  3. Reid K et al. (1996) Multiple roles for endothelin in melanocyte development: regulation of progenitor number and stimulation of differentiation. Development 122: 3911-9 PubMed GONUTS page
  4. 4.0 4.1 MAYER TC & MALTBY EL (1964) AN EXPERIMENTAL INVESTIGATION OF PATTERN DEVELOPMENT IN LETHAL SPOTTING AND BELTED MOUSE EMBRYOS. Dev Biol 22: 269-86 PubMed GONUTS page
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