GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
MGI:Eda
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Eda ( synonyms: Ed1, Eda-A1, Eda-A2, EDA1 ) | |
| Protein Name(s) | ectodysplasin-A, | |
| External Links | ||
| MGI | MGI:1195272 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001942 |
hair follicle development |
MGI:MGI:3813383 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1352474 |
P |
From MGI |
||
| GO:0001942 |
hair follicle development |
MGI:MGI:3813383 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1856197 |
P |
From MGI |
||
| GO:0001942 |
hair follicle development |
MGI:MGI:54784 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1856197 |
P |
From MGI |
||
| GO:0005102 |
receptor binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005164 |
tumor necrosis factor receptor binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005576 |
extracellular region |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0964 |
C |
From MGI |
||
| GO:0005581 |
collagen |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0176 |
C |
From MGI |
||
| GO:0005789 |
endoplasmic reticulum membrane |
MGI:MGI:1349243 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-1003 |
C |
From MGI |
||
| GO:0005887 |
integral to plasma membrane |
MGI:MGI:1349243 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0006955 |
immune response |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007160 |
cell-matrix adhesion |
MGI:MGI:1349243 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0007275 |
multicellular organismal development |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0217 |
P |
From MGI |
||
| GO:0010467 |
gene expression |
MGI:MGI:3770480 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1856202 |
P |
From MGI |
||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016020 |
membrane |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0016021 |
integral to membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From MGI |
||
| GO:0030154 |
cell differentiation |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0221 |
P |
From MGI |
||
| GO:0042346 |
positive regulation of NF-kappaB import into nucleus |
MGI:MGI:3617077 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0042475 |
odontogenesis of dentin-containing tooth |
MGI:MGI:3612936 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1856197 |
P |
From MGI |
||
| GO:0042475 |
odontogenesis of dentin-containing tooth |
MGI:MGI:61212 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1856197 |
P |
From MGI |
||
| GO:0043123 |
positive regulation of I-kappaB kinase/NF-kappaB cascade |
MGI:MGI:3813383 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1856197 |
P |
From MGI |
||
| GO:0043473 |
pigmentation |
MGI:MGI:53773 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1856197 |
P |
From MGI |
||
| GO:0043473 |
pigmentation |
MGI:MGI:65389 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1858152 |
P |
From MGI |
||
| GO:0043588 |
skin development |
MGI:MGI:3770480 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1856202 |
P |
From MGI |
||
| GO:0045177 |
apical part of cell |
MGI:MGI:3617077 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0051092 |
positive regulation of NF-kappaB transcription factor activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0060662 |
salivary gland cavitation |
MGI:MGI:3617077 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0060789 |
hair follicle placode formation |
MGI:MGI:4355652 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:88276 |
P |
From MGI |
||
| GO:0061153 |
trachea gland development |
MGI:MGI:3703377 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1856197 |
P |
From MGI |
||
| GO:0090263 |
positive regulation of canonical Wnt receptor signaling pathway |
MGI:MGI:4355652 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1856197 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Pispa J et al. (2008) Edar and Troy signalling pathways act redundantly to regulate initiation of hair follicle development. Hum Mol Genet 17: 3380-91 PubMed GONUTS page
- ↑ Crocker M & Cattanach BM (1979) The genetics of Sleek: a possible regulatory mutation of the tabby-crinkled-downless syndrome. Genet Res 34: 231-8 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Mikkola ML et al. (1999) Ectodysplasin, a protein required for epithelial morphogenesis, is a novel TNF homologue and promotes cell-matrix adhesion. Mech Dev 88: 133-46 PubMed GONUTS page
- ↑ 4.0 4.1 Cui CY et al. (2007) Lymphotoxin-beta regulates periderm differentiation during embryonic skin development. Hum Mol Genet 16: 2583-90 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 Jaskoll T et al. (2003) Ectodysplasin receptor-mediated signaling is essential for embryonic submandibular salivary gland development. Anat Rec A Discov Mol Cell Evol Biol 271: 322-31 PubMed GONUTS page
- ↑ Miard S et al. (1999) Alterations in the incisor development in the Tabby mouse. Int J Dev Biol 43: 517-29 PubMed GONUTS page
- ↑ Grüneberg H (1965) Genes and genotypes affecting the teeth of the mouse. J Embryol Exp Morphol 14: 137-59 PubMed GONUTS page
- ↑ Cattanach BM et al. (1972) A comparative study of the coats of chimaeric mice and those of heterozygotes for X-linked genes. Genet Res 19: 213-28 PubMed GONUTS page
- ↑ 9.0 9.1 Zhang Y et al. (2009) Reciprocal requirements for EDA/EDAR/NF-kappaB and Wnt/beta-catenin signaling pathways in hair follicle induction. Dev Cell 17: 49-61 PubMed GONUTS page
- ↑ Rawlins EL & Hogan BL (2005) Intercellular growth factor signaling and the development of mouse tracheal submucosal glands. Dev Dyn 233: 1378-85 PubMed GONUTS page
