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MGI:Ecsit

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Ecsit ( synonyms: Sitpec )
Protein Name(s) ECSIT homolog (Drosophila),
External Links
MGI MGI:1349469

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001707

mesoderm formation

MGI:MGI:2682456
PMID:14633973[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2683025

P

From MGI

GO:0003700

sequence-specific DNA binding transcription factor activity

MGI:MGI:2682456
PMID:14633973[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0004871

signal transducer activity

MGI:MGI:1344119
PMID:10465784[2]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005515

protein binding

MGI:MGI:1344119
PMID:10465784[2]

IPI: Inferred from Physical Interaction

UniProtKB:P70196
UniProtKB:Q9Y4K3

F

From MGI

GO:0005515

protein binding

MGI:MGI:3688344
PMID:15102471[3]

IPI: Inferred from Physical Interaction

UniProtKB:P70196

F

From MGI

GO:0005634

nucleus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:E9PAN9

C

From MGI

GO:0005667

transcription factor complex

MGI:MGI:2682456
PMID:14633973[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:E9PAN9

C

From MGI

GO:0005739

mitochondrion

MGI:MGI:3852644
PMID:18614015[4]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005739

mitochondrion

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9BQ95

C

From MGI

GO:0006357

regulation of transcription from RNA polymerase II promoter

MGI:MGI:2682456
PMID:14633973[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0006357

regulation of transcription from RNA polymerase II promoter

MGI:MGI:2682456
PMID:14633973[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0007178

transmembrane receptor protein serine/threonine kinase signaling pathway

MGI:MGI:1344119
PMID:10465784[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0007178

transmembrane receptor protein serine/threonine kinase signaling pathway

MGI:MGI:1344119
PMID:10465784[2]

IPI: Inferred from Physical Interaction

UniProtKB:P70196

P

From MGI

GO:0016651

oxidoreductase activity, acting on NADH or NADPH

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9BQ95

F

From MGI

GO:0030509

BMP signaling pathway

MGI:MGI:2682456
PMID:14633973[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0045087

innate immune response

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0399

P

From MGI

GO:0051341

regulation of oxidoreductase activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9BQ95

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 1.5 Xiao C et al. (2003) Ecsit is required for Bmp signaling and mesoderm formation during mouse embryogenesis. Genes Dev 17: 2933-49 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Kopp E et al. (1999) ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathway. Genes Dev 13: 2059-71 PubMed GONUTS page
  3. Papin J & Subramaniam S (2004) Bioinformatics and cellular signaling. Curr Opin Biotechnol 15: 78-81 PubMed GONUTS page
  4. Pagliarini DJ et al. (2008) A mitochondrial protein compendium elucidates complex I disease biology. Cell 134: 112-23 PubMed GONUTS page
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