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MGI:Dyrk3

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Dyrk3
Protein Name(s) dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3,
External Links
MGI MGI:1330300

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

From MGI

GO:0000287

magnesium ion binding

MGI:MGI:3715063
PMID:12356771[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0000287

magnesium ion binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O43781

F

From MGI

GO:0004672

protein kinase activity

MGI:MGI:3715063
PMID:12356771[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0004672

protein kinase activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O43781

F

From MGI

GO:0004674

protein serine/threonine kinase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0723

F

From MGI

GO:0004674

protein serine/threonine kinase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR008271

F

From MGI

GO:0004712

protein serine/threonine/tyrosine kinase activity

MGI:MGI:2152096

IEA: Inferred from Electronic Annotation

EC:2.7.12.1

F

From MGI

GO:0004713

protein tyrosine kinase activity

MGI:MGI:1303167
PMID:9748265[2]

ISA: Inferred from Sequence Alignment

EMBL:Y12735

F

From MGI

GO:0005515

protein binding

MGI:MGI:4838949
PMID:20167603[3]

IPI: Inferred from Physical Interaction

UniProtKB:Q923E4

F

From MGI

GO:0005524

ATP binding

MGI:MGI:3715063
PMID:12356771[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005524

ATP binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O43781

F

From MGI

GO:0005634

nucleus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O43781

C

From MGI

GO:0006468

protein phosphorylation

MGI:MGI:3715063
PMID:12356771[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0006468

protein phosphorylation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O43781

P

From MGI

GO:0016301

kinase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

F

From MGI

GO:0016310

phosphorylation

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

P

From MGI

GO:0016740

transferase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0808

F

From MGI

GO:0016772

transferase activity, transferring phosphorus-containing groups

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011009

F

From MGI

GO:0018108

peptidyl-tyrosine phosphorylation

MGI:MGI:1303167
PMID:9748265[2]

ISA: Inferred from Sequence Alignment

EMBL:Y12735

P

From MGI

GO:0030218

erythrocyte differentiation

MGI:MGI:3715071
PMID:16524748[4]

IDA: Inferred from Direct Assay

P

From MGI

GO:0030218

erythrocyte differentiation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O43781

P

From MGI

GO:0046872

metal ion binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Li K et al. (2002) DYRK3 activation, engagement of protein kinase A/cAMP response element-binding protein, and modulation of progenitor cell survival. J Biol Chem 277: 47052-60 PubMed GONUTS page
  2. 2.0 2.1 Becker W et al. (1998) Sequence characteristics, subcellular localization, and substrate specificity of DYRK-related kinases, a novel family of dual specificity protein kinases. J Biol Chem 273: 25893-902 PubMed GONUTS page
  3. Guo X et al. (2010) DYRK1A and DYRK3 promote cell survival through phosphorylation and activation of SIRT1. J Biol Chem 285: 13223-32 PubMed GONUTS page
  4. Wojchowski DM et al. (2006) Erythropoietin-dependent erythropoiesis: New insights and questions. Blood Cells Mol Dis 36: 232-8 PubMed GONUTS page
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