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MGI:Dync2h1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Dync2h1 ( synonyms: DHC1b, DHC2, Dnchc2 )
Protein Name(s) dynein cytoplasmic 2 heavy chain 1,
External Links
MGI MGI:107736

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

From MGI

GO:0000166

nucleotide binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR003593

F

From MGI

GO:0003774

motor activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0243

F

From MGI

GO:0003777

microtubule motor activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR004273

F

From MGI

GO:0005524

ATP binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0067

F

From MGI

GO:0005524

ATP binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011704

F

From MGI

GO:0005737

cytoplasm

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0963

C

From MGI

GO:0005794

Golgi apparatus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q8NCM8

C

From MGI

GO:0005856

cytoskeleton

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0206

C

From MGI

GO:0005874

microtubule

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0493

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-1003

C

From MGI

GO:0005929

cilium

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0969

C

From MGI

GO:0006200

ATP catabolic process

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011704

P

From MGI

GO:0007018

microtubule-based movement

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR004273

P

From MGI

GO:0007030

Golgi organization

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q8NCM8

P

From MGI

GO:0007275

multicellular organismal development

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0217

P

From MGI

GO:0007368

determination of left/right symmetry

MGI:MGI:3577662
PMID:15755804[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3578144

P

From MGI

GO:0007368

determination of left/right symmetry

MGI:MGI:3588600
PMID:16061793[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3578144

P

From MGI

GO:0007368

determination of left/right symmetry

MGI:MGI:3610248
PMID:16229832[3]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0008105

asymmetric protein localization

MGI:MGI:3610248
PMID:16229832[3]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0008152

metabolic process

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0243

P

From MGI

GO:0008152

metabolic process

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR003593

P

From MGI

GO:0009953

dorsal/ventral pattern formation

MGI:MGI:3577662
PMID:15755804[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3578144

P

From MGI

GO:0009953

dorsal/ventral pattern formation

MGI:MGI:3588600
PMID:16061793[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3578144

P

From MGI

GO:0009953

dorsal/ventral pattern formation

MGI:MGI:3610248
PMID:16229832[3]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016485

protein processing

MGI:MGI:3588600
PMID:16061793[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3578144

P

From MGI

GO:0016485

protein processing

MGI:MGI:3610248
PMID:16229832[3]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0016887

ATPase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011704

F

From MGI

GO:0017111

nucleoside-triphosphatase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR003593

F

From MGI

GO:0030030

cell projection organization

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0970

P

From MGI

GO:0030286

dynein complex

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0243

C

From MGI

GO:0030286

dynein complex

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR004273

C

From MGI

GO:0030326

embryonic limb morphogenesis

MGI:MGI:3610248
PMID:16229832[3]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0030900

forebrain development

MGI:MGI:3610248
PMID:16229832[3]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0031512

motile primary cilium

MGI:MGI:5009180
PMID:12802074[4]

IDA: Inferred from Direct Assay

C

From MGI

GO:0035085

cilium axoneme

MGI:MGI:5009180
PMID:12802074[4]

IDA: Inferred from Direct Assay

C

From MGI

GO:0042384

cilium assembly

MGI:MGI:3588600
PMID:16061793[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3578144

P

From MGI

GO:0042384

cilium assembly

MGI:MGI:3610248
PMID:16229832[3]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0042995

cell projection

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0966

C

From MGI

GO:0045177

apical part of cell

MGI:MGI:5009180
PMID:12802074[4]

IDA: Inferred from Direct Assay

C

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 García-García MJ et al. (2005) Analysis of mouse embryonic patterning and morphogenesis by forward genetics. Proc Natl Acad Sci U S A 102: 5913-9 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Huangfu D & Anderson KV (2005) Cilia and Hedgehog responsiveness in the mouse. Proc Natl Acad Sci U S A 102: 11325-30 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 3.5 3.6 May SR et al. (2005) Loss of the retrograde motor for IFT disrupts localization of Smo to cilia and prevents the expression of both activator and repressor functions of Gli. Dev Biol 287: 378-89 PubMed GONUTS page
  4. 4.0 4.1 4.2 Perrone CA et al. (2003) A novel dynein light intermediate chain colocalizes with the retrograde motor for intraflagellar transport at sites of axoneme assembly in chlamydomonas and Mammalian cells. Mol Biol Cell 14: 2041-56 PubMed GONUTS page
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