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MGI:Dscam

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Dscam
Protein Name(s) Down syndrome cell adhesion molecule,
External Links
MGI MGI:1196281

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005515

protein binding

MGI:MGI:3829111
PMID:18585357[1]

IPI: Inferred from Physical Interaction

UniProtKB:P70211
UniProtKB:Q63155
UniProtKB:Q90922

F

From MGI

GO:0005886

plasma membrane

MGI:MGI:4441243
PMID:19196994[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0007155

cell adhesion

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0130

P

From MGI

GO:0007162

negative regulation of cell adhesion

MGI:MGI:4413613
PMID:19945391[3]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0007399

nervous system development

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0524

P

From MGI

GO:0007626

locomotory behavior

MGI:MGI:3768917
PMID:18216855[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3761008

P

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016021

integral to membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0812

C

From MGI

GO:0030424

axon

MGI:MGI:4441243
PMID:19196994[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0030426

growth cone

MGI:MGI:4441243
PMID:19196994[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0042327

positive regulation of phosphorylation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O60469

P

From MGI

GO:0048813

dendrite morphogenesis

MGI:MGI:3768917
PMID:18216855[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3761008

P

From MGI

GO:0048842

positive regulation of axon extension involved in axon guidance

MGI:MGI:3829111
PMID:18585357[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0048842

positive regulation of axon extension involved in axon guidance

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_598271

P

From MGI

GO:0048842

positive regulation of axon extension involved in axon guidance

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O60469

P

From MGI

GO:0060060

post-embryonic retina morphogenesis in camera-type eye

MGI:MGI:3768917
PMID:18216855[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3761008

P

From MGI

GO:0070593

dendrite self-avoidance

MGI:MGI:4413613
PMID:19945391[3]

IMP: Inferred from Mutant Phenotype

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Ly A et al. (2008) DSCAM is a netrin receptor that collaborates with DCC in mediating turning responses to netrin-1. Cell 133: 1241-54 PubMed GONUTS page
  2. 2.0 2.1 2.2 Liu G et al. (2009) DSCAM functions as a netrin receptor in commissural axon pathfinding. Proc Natl Acad Sci U S A 106: 2951-6 PubMed GONUTS page
  3. 3.0 3.1 Fuerst PG et al. (2009) DSCAM and DSCAML1 function in self-avoidance in multiple cell types in the developing mouse retina. Neuron 64: 484-97 PubMed GONUTS page
  4. 4.0 4.1 4.2 Fuerst PG et al. (2008) Neurite arborization and mosaic spacing in the mouse retina require DSCAM. Nature 451: 470-4 PubMed GONUTS page
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