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MGI:Dnmt3l
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Dnmt3l ( synonyms: D6Ertd14e, ecat7 ) | |
| Protein Name(s) | DNA (cytosine-5-)-methyltransferase 3-like, | |
| External Links | ||
| MGI | MGI:1859287 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000794 |
condensed nuclear chromosome |
MGI:MGI:3623538 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0001701 |
in utero embryonic development |
MGI:MGI:2178074 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2447127 |
P |
From MGI |
||
| GO:0005515 |
protein binding |
MGI:MGI:2178074 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3623538 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3768461 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005720 |
nuclear heterochromatin |
MGI:MGI:2178074 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:2178074 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:3623538 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005829 |
cytosol |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0008047 |
enzyme activator activity |
MGI:MGI:2154458 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0008047 |
enzyme activator activity |
MGI:MGI:3623538 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0008168 |
methyltransferase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0489 |
F |
From MGI |
||
| GO:0016740 |
transferase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0808 |
F |
From MGI |
||
| GO:0019899 |
enzyme binding |
MGI:MGI:3687896 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From MGI |
|||
| GO:0019899 |
enzyme binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0032259 |
methylation |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0489 |
P |
From MGI |
||
| GO:0043085 |
positive regulation of catalytic activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
MGI:MGI:3687896 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From MGI |
|||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0046872 |
metal ion binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0479 |
F |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Xie ZH et al. (2006) Mutations in DNA methyltransferase DNMT3B in ICF syndrome affect its regulation by DNMT3L. Hum Mol Genet 15: 1375-85 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Hata K et al. (2002) Dnmt3L cooperates with the Dnmt3 family of de novo DNA methyltransferases to establish maternal imprints in mice. Development 129: 1983-93 PubMed GONUTS page
- ↑ Li JY et al. (2007) Synergistic function of DNA methyltransferases Dnmt3a and Dnmt3b in the methylation of Oct4 and Nanog. Mol Cell Biol 27: 8748-59 PubMed GONUTS page
- ↑ 4.0 4.1 Deplus R et al. (2002) Dnmt3L is a transcriptional repressor that recruits histone deacetylase. Nucleic Acids Res 30: 3831-8 PubMed GONUTS page
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