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MGI:Dnajc3

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Dnajc3 ( synonyms: Dnajc3, Dnajc3a, Dnajc3b, mp58, p58IPK, Prkri )
Protein Name(s) DnaJ (Hsp40) homolog, subfamily C, member 3,
External Links
MGI MGI:107373

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004860

protein kinase inhibitor activity

MGI:MGI:80529
PMID:8666242[1]

ISS: Inferred from Sequence or Structural Similarity

F

From MGI

GO:0005737

cytoplasm

MGI:MGI:80529
PMID:8666242[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005783

endoplasmic reticulum

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0256

C

From MGI

GO:0005788

endoplasmic reticulum lumen

MGI:MGI:4418606
PMID:18923430[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005829

cytosol

MGI:MGI:4418606
PMID:18923430[2]

TAS: Traceable Author Statement

C

From MGI

GO:0006457

protein folding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR003095

P

From MGI

GO:0006469

negative regulation of protein kinase activity

MGI:MGI:80529
PMID:8666242[1]

ISS: Inferred from Sequence or Structural Similarity

P

From MGI

GO:0006986

response to unfolded protein

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0834

P

From MGI

GO:0030968

endoplasmic reticulum unfolded protein response

MGI:MGI:4418606
PMID:18923430[2]

IC: Inferred by Curator

GO:0051787

P

From MGI

GO:0031072

heat shock protein binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001623
InterPro:IPR003095

F

From MGI

GO:0051082

unfolded protein binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR003095

F

From MGI

GO:0051087

chaperone binding

MGI:MGI:4418606
PMID:18923430[2]

IPI: Inferred from Physical Interaction

UniProtKB:P20029

F

From MGI

GO:0051603

proteolysis involved in cellular protein catabolic process

MGI:MGI:4418606
PMID:18923430[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0051787

misfolded protein binding

MGI:MGI:4418606
PMID:18923430[2]

IDA: Inferred from Direct Assay

F

From MGI

colocalizes_with

GO:0031205

endoplasmic reticulum Sec complex

MGI:MGI:3692677
PMID:16923392[3]

IDA: Inferred from Direct Assay

C

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Korth MJ et al. (1996) Cloning, expression, and cellular localization of the oncogenic 58-kDa inhibitor of the RNA-activated human and mouse protein kinase. Gene 170: 181-8 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 Petrova K et al. (2008) Regulated association of misfolded endoplasmic reticulum lumenal proteins with P58/DNAJc3. EMBO J 27: 2862-72 PubMed GONUTS page
  3. Oyadomari S et al. (2006) Cotranslocational degradation protects the stressed endoplasmic reticulum from protein overload. Cell 126: 727-39 PubMed GONUTS page
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