![]()
GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
MGI:Dnajc3
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Dnajc3 ( synonyms: Dnajc3, Dnajc3a, Dnajc3b, mp58, p58IPK, Prkri ) | |
| Protein Name(s) | DnaJ (Hsp40) homolog, subfamily C, member 3, | |
| External Links | ||
| MGI | MGI:107373 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004860 |
protein kinase inhibitor activity |
MGI:MGI:80529 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:80529 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005783 |
endoplasmic reticulum |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0256 |
C |
From MGI |
||
| GO:0005788 |
endoplasmic reticulum lumen |
MGI:MGI:4418606 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005829 |
cytosol |
MGI:MGI:4418606 |
TAS: Traceable Author Statement |
C |
From MGI |
|||
| GO:0006457 |
protein folding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0006469 |
negative regulation of protein kinase activity |
MGI:MGI:80529 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From MGI |
|||
| GO:0006986 |
response to unfolded protein |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0834 |
P |
From MGI |
||
| GO:0030968 |
endoplasmic reticulum unfolded protein response |
MGI:MGI:4418606 |
IC: Inferred by Curator |
GO:0051787 |
P |
From MGI |
||
| GO:0031072 |
heat shock protein binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0051082 |
unfolded protein binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0051087 |
chaperone binding |
MGI:MGI:4418606 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0051603 |
proteolysis involved in cellular protein catabolic process |
MGI:MGI:4418606 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0051787 |
misfolded protein binding |
MGI:MGI:4418606 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
|
colocalizes_with |
GO:0031205 |
endoplasmic reticulum Sec complex |
MGI:MGI:3692677 |
IDA: Inferred from Direct Assay |
C |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Korth MJ et al. (1996) Cloning, expression, and cellular localization of the oncogenic 58-kDa inhibitor of the RNA-activated human and mouse protein kinase. Gene 170: 181-8 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 Petrova K et al. (2008) Regulated association of misfolded endoplasmic reticulum lumenal proteins with P58/DNAJc3. EMBO J 27: 2862-72 PubMed GONUTS page
- ↑ Oyadomari S et al. (2006) Cotranslocational degradation protects the stressed endoplasmic reticulum from protein overload. Cell 126: 727-39 PubMed GONUTS page