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MGI:Dmc1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Dmc1 ( synonyms: Dmc1, Dmc1h, Mei11, sgdp )
Protein Name(s) DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast),
External Links
MGI MGI:105393

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

From MGI

GO:0000166

nucleotide binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR003593
InterPro:IPR010995

F

From MGI

GO:0000239

pachytene

MGI:MGI:3719060
PMID:17696610[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2176331

P

From MGI

GO:0000781

chromosome, telomeric region

MGI:MGI:4440771
PMID:20336070[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0000794

condensed nuclear chromosome

MGI:MGI:3774244
PMID:18316482[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0000794

condensed nuclear chromosome

MGI:MGI:3794139
PMID:18283110[4]

IDA: Inferred from Direct Assay

C

From MGI

GO:0000794

condensed nuclear chromosome

MGI:MGI:4457793
PMID:20551173[5]

IDA: Inferred from Direct Assay

C

From MGI

GO:0001541

ovarian follicle development

MGI:MGI:3529751
PMID:15640358[6]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2176331

P

From MGI

GO:0001556

oocyte maturation

MGI:MGI:3719060
PMID:17696610[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2176331

P

From MGI

GO:0003677

DNA binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0238

F

From MGI

GO:0003677

DNA binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011940
InterPro:IPR020588
InterPro:IPR003583
InterPro:IPR020587

F

From MGI

GO:0005524

ATP binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0067

F

From MGI

GO:0005524

ATP binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011940
InterPro:IPR020588
InterPro:IPR020587

F

From MGI

GO:0005634

nucleus

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From MGI

GO:0005634

nucleus

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011940

C

From MGI

GO:0006200

ATP catabolic process

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011940
InterPro:IPR020588
InterPro:IPR020587

P

From MGI

GO:0006259

DNA metabolic process

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR020588
InterPro:IPR020587

P

From MGI

GO:0006281

DNA repair

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR003583

P

From MGI

GO:0007049

cell cycle

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0131

P

From MGI

GO:0007126

meiosis

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0469

P

From MGI

GO:0007131

reciprocal meiotic recombination

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011940

P

From MGI

GO:0007141

male meiosis I

MGI:MGI:3719060
PMID:17696610[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2176331

P

From MGI

GO:0007276

gamete generation

MGI:MGI:2678891
PMID:12855593[7]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2177010

P

From MGI

GO:0007283

spermatogenesis

MGI:MGI:2678891
PMID:12855593[7]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2177010

P

From MGI

GO:0007286

spermatid development

MGI:MGI:3719060
PMID:17696610[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2176331

P

From MGI

GO:0008094

DNA-dependent ATPase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011940
InterPro:IPR020588
InterPro:IPR020587

F

From MGI

GO:0017111

nucleoside-triphosphatase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR003593

F

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Li XC & Schimenti JC (2007) Mouse pachytene checkpoint 2 (trip13) is required for completing meiotic recombination but not synapsis. PLoS Genet 3: e130 PubMed GONUTS page
  2. Zalzman M et al. (2010) Zscan4 regulates telomere elongation and genomic stability in ES cells. Nature 464: 858-63 PubMed GONUTS page
  3. Yang F et al. (2008) Meiotic failure in male mice lacking an X-linked factor. Genes Dev 22: 682-91 PubMed GONUTS page
  4. Yang F et al. (2008) Mouse TEX15 is essential for DNA double-strand break repair and chromosomal synapsis during male meiosis. J Cell Biol 180: 673-9 PubMed GONUTS page
  5. Kumar R et al. (2010) Functional conservation of Mei4 for meiotic DNA double-strand break formation from yeasts to mice. Genes Dev 24: 1266-80 PubMed GONUTS page
  6. Di Giacomo M et al. (2005) Distinct DNA-damage-dependent and -independent responses drive the loss of oocytes in recombination-defective mouse mutants. Proc Natl Acad Sci U S A 102: 737-42 PubMed GONUTS page
  7. 7.0 7.1 Ward JO et al. (2003) Toward the genetics of mammalian reproduction: induction and mapping of gametogenesis mutants in mice. Biol Reprod 69: 1615-25 PubMed GONUTS page
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