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MGI:Dmc1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Dmc1 ( synonyms: Dmc1, Dmc1h, Mei11, sgdp ) | |
| Protein Name(s) | DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast), | |
| External Links | ||
| MGI | MGI:105393 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000166 |
nucleotide binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0547 |
F |
From MGI |
||
| GO:0000166 |
nucleotide binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0000239 |
pachytene |
MGI:MGI:3719060 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2176331 |
P |
From MGI |
||
| GO:0000781 |
chromosome, telomeric region |
MGI:MGI:4440771 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0000794 |
condensed nuclear chromosome |
MGI:MGI:3774244 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0000794 |
condensed nuclear chromosome |
MGI:MGI:3794139 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0000794 |
condensed nuclear chromosome |
MGI:MGI:4457793 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0001541 |
ovarian follicle development |
MGI:MGI:3529751 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2176331 |
P |
From MGI |
||
| GO:0001556 |
oocyte maturation |
MGI:MGI:3719060 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2176331 |
P |
From MGI |
||
| GO:0003677 |
DNA binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0238 |
F |
From MGI |
||
| GO:0003677 |
DNA binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
InterPro:IPR011940 |
F |
From MGI |
||
| GO:0005524 |
ATP binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0067 |
F |
From MGI |
||
| GO:0005524 |
ATP binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0539 |
C |
From MGI |
||
| GO:0005634 |
nucleus |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0006200 |
ATP catabolic process |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0006259 |
DNA metabolic process |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0006281 |
DNA repair |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007049 |
cell cycle |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0131 |
P |
From MGI |
||
| GO:0007126 |
meiosis |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0469 |
P |
From MGI |
||
| GO:0007131 |
reciprocal meiotic recombination |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007141 |
male meiosis I |
MGI:MGI:3719060 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2176331 |
P |
From MGI |
||
| GO:0007276 |
gamete generation |
MGI:MGI:2678891 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2177010 |
P |
From MGI |
||
| GO:0007283 |
spermatogenesis |
MGI:MGI:2678891 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2177010 |
P |
From MGI |
||
| GO:0007286 |
spermatid development |
MGI:MGI:3719060 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2176331 |
P |
From MGI |
||
| GO:0008094 |
DNA-dependent ATPase activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0017111 |
nucleoside-triphosphatase activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Li XC & Schimenti JC (2007) Mouse pachytene checkpoint 2 (trip13) is required for completing meiotic recombination but not synapsis. PLoS Genet 3: e130 PubMed GONUTS page
- ↑ Zalzman M et al. (2010) Zscan4 regulates telomere elongation and genomic stability in ES cells. Nature 464: 858-63 PubMed GONUTS page
- ↑ Yang F et al. (2008) Meiotic failure in male mice lacking an X-linked factor. Genes Dev 22: 682-91 PubMed GONUTS page
- ↑ Yang F et al. (2008) Mouse TEX15 is essential for DNA double-strand break repair and chromosomal synapsis during male meiosis. J Cell Biol 180: 673-9 PubMed GONUTS page
- ↑ Kumar R et al. (2010) Functional conservation of Mei4 for meiotic DNA double-strand break formation from yeasts to mice. Genes Dev 24: 1266-80 PubMed GONUTS page
- ↑ Di Giacomo M et al. (2005) Distinct DNA-damage-dependent and -independent responses drive the loss of oocytes in recombination-defective mouse mutants. Proc Natl Acad Sci U S A 102: 737-42 PubMed GONUTS page
- ↑ 7.0 7.1 Ward JO et al. (2003) Toward the genetics of mammalian reproduction: induction and mapping of gametogenesis mutants in mice. Biol Reprod 69: 1615-25 PubMed GONUTS page