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MGI:Dlc1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Dlc1 ( synonyms: Arhgap7, p122-RhoGAP, STARD12 ) | |
| Protein Name(s) | deleted in liver cancer 1, | |
| External Links | ||
| MGI | MGI:1354949 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001843 |
neural tube closure |
MGI:MGI:3529660 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3529997 |
P |
From MGI |
||
| GO:0003007 |
heart morphogenesis |
MGI:MGI:3529660 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3529997 |
P |
From MGI |
||
| GO:0005096 |
GTPase activator activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0343 |
F |
From MGI |
||
| GO:0005100 |
Rho GTPase activator activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005100 |
Rho GTPase activator activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005622 |
intracellular |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005901 |
caveola |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005925 |
focal adhesion |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006917 |
induction of apoptosis |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006919 |
activation of cysteine-type endopeptidase activity involved in apoptotic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0007010 |
cytoskeleton organization |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0007165 |
signal transduction |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007202 |
activation of phospholipase C activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0008285 |
negative regulation of cell proliferation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0008360 |
regulation of cell shape |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0017166 |
vinculin binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0021575 |
hindbrain morphogenesis |
MGI:MGI:3529660 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3529997 |
P |
From MGI |
||
| GO:0030036 |
actin cytoskeleton organization |
MGI:MGI:3529660 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3529997 |
P |
From MGI |
||
| GO:0030336 |
negative regulation of cell migration |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0030900 |
forebrain development |
MGI:MGI:3529660 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3529997 |
P |
From MGI |
||
| GO:0032321 |
positive regulation of Rho GTPase activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0032321 |
positive regulation of Rho GTPase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0032956 |
regulation of actin cytoskeleton organization |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0035024 |
negative regulation of Rho protein signal transduction |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0035307 |
positive regulation of protein dephosphorylation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0042169 |
SH2 domain binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0043274 |
phospholipase binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0045121 |
membrane raft |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0048041 |
focal adhesion assembly |
MGI:MGI:3529660 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3529997 |
P |
From MGI |
||
| GO:0051497 |
negative regulation of stress fiber assembly |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
|
colocalizes_with |
GO:0001725 |
stress fiber |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
||
|
colocalizes_with |
GO:0005884 |
actin filament |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
||
|
colocalizes_with |
GO:0005925 |
focal adhesion |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Durkin ME et al. (2005) DLC-1, a Rho GTPase-activating protein with tumor suppressor function, is essential for embryonic development. FEBS Lett 579: 1191-6 PubMed GONUTS page
