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MGI:Diablo
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Diablo ( synonyms: Smac ) | |
| Protein Name(s) | diablo homolog (Drosophila), | |
| External Links | ||
| MGI | MGI:1913843 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005737 |
cytoplasm |
MGI:MGI:3577836 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:3587135 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005739 |
mitochondrion |
MGI:MGI:2681362 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005739 |
mitochondrion |
MGI:MGI:2682130 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005739 |
mitochondrion |
MGI:MGI:3577836 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005739 |
mitochondrion |
MGI:MGI:3587135 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005739 |
mitochondrion |
MGI:MGI:3589497 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005739 |
mitochondrion |
MGI:MGI:3801240 |
ISS: Inferred from Sequence or Structural Similarity |
RefSeq:NP_001008293 |
C |
From MGI |
||
| GO:0005739 |
mitochondrion |
MGI:MGI:3852644 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005739 |
mitochondrion |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005758 |
mitochondrial intermembrane space |
MGI:MGI:3703929 |
ISO: Inferred from Sequence Orthology |
RefSeq:NP_001008293 |
C |
From MGI |
||
| GO:0006915 |
apoptotic process |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0053 |
P |
From MGI |
||
| GO:0006917 |
induction of apoptosis |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0006919 |
activation of cysteine-type endopeptidase activity involved in apoptotic process |
MGI:MGI:3587135 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0006919 |
activation of cysteine-type endopeptidase activity involved in apoptotic process |
MGI:MGI:3587135 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0008631 |
induction of apoptosis by oxidative stress |
MGI:MGI:3587135 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0009898 |
internal side of plasma membrane |
MGI:MGI:4462284 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0035631 |
CD40 receptor complex |
MGI:MGI:4462284 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0043065 |
positive regulation of apoptotic process |
MGI:MGI:2681362 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0097193 |
intrinsic apoptotic signaling pathway |
MGI:MGI:5306292 |
TAS: Traceable Author Statement |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Mendoza FJ et al. (2005) MEKK1-induced apoptosis is mediated by Smac/Diablo release from the mitochondria. Biochem Biophys Res Commun 331: 1089-98 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Jiang B et al. (2005) Role of Smac/DIABLO in hydrogen peroxide-induced apoptosis in C2C12 myogenic cells. Free Radic Biol Med 39: 658-67 PubMed GONUTS page
- ↑ 3.0 3.1 Potts PR et al. (2003) Critical function of endogenous XIAP in regulating caspase activation during sympathetic neuronal apoptosis. J Cell Biol 163: 789-99 PubMed GONUTS page
- ↑ Mootha VK et al. (2003) Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Cell 115: 629-40 PubMed GONUTS page
- ↑ Burri L et al. (2005) Mature DIABLO/Smac is produced by the IMP protease complex on the mitochondrial inner membrane. Mol Biol Cell 16: 2926-33 PubMed GONUTS page
- ↑ Rardin MJ et al. (2008) Dual specificity phosphatases 18 and 21 target to opposing sides of the mitochondrial inner membrane. J Biol Chem 283: 15440-50 PubMed GONUTS page
- ↑ Pagliarini DJ et al. (2008) A mitochondrial protein compendium elucidates complex I disease biology. Cell 134: 112-23 PubMed GONUTS page
- ↑ Wiley SE et al. (2007) MitoNEET is an iron-containing outer mitochondrial membrane protein that regulates oxidative capacity. Proc Natl Acad Sci U S A 104: 5318-23 PubMed GONUTS page
- ↑ 9.0 9.1 Hostager BS et al. (2010) HOIL-1L interacting protein (HOIP) as an NF-kappaB regulating component of the CD40 signaling complex. PLoS One 5: e11380 PubMed GONUTS page
- ↑ Galluzzi L et al. (2008) No death without life: vital functions of apoptotic effectors. Cell Death Differ 15: 1113-23 PubMed GONUTS page
