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MGI:Dhh

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Dhh
Protein Name(s) desert hedgehog,
External Links
MGI MGI:94891

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005113

patched binding

MGI:MGI:1313055
PMID:9811851[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q13635
UniProtKB:Q9Y6C5

F

From MGI

GO:0005509

calcium ion binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O43323

F

From MGI

GO:0005515

protein binding

MGI:MGI:1333378
PMID:10050855[2]

IPI: Inferred from Physical Interaction

UniProtKB:Q9WU59

F

From MGI

GO:0005576

extracellular region

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0964

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-1003

C

From MGI

GO:0006508

proteolysis

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0645

P

From MGI

GO:0006508

proteolysis

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001767

P

From MGI

GO:0007154

cell communication

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001657

P

From MGI

GO:0007267

cell-cell signaling

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000320

P

From MGI

GO:0007275

multicellular organismal development

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0217

P

From MGI

GO:0007275

multicellular organismal development

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001657
InterPro:IPR000320

P

From MGI

GO:0007286

spermatid development

MGI:MGI:3769860
PMID:17495005[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1934259

P

From MGI

GO:0008233

peptidase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0645

F

From MGI

GO:0008233

peptidase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001767

F

From MGI

GO:0008270

zinc ion binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O43323

F

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016539

intein-mediated protein splicing

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR006141

P

From MGI

GO:0016787

hydrolase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0378

F

From MGI

GO:0022402

cell cycle process

MGI:MGI:3769860
PMID:17495005[3]

IGI: Inferred from Genetic Interaction

MGI:MGI:1095403

P

From MGI

GO:0030238

male sex determination

MGI:MGI:3769860
PMID:17495005[3]

IGI: Inferred from Genetic Interaction

MGI:MGI:1095403

P

From MGI

GO:0033327

Leydig cell differentiation

MGI:MGI:2450504
PMID:12050120[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1934259

P

From MGI

GO:0033327

Leydig cell differentiation

MGI:MGI:3769860
PMID:17495005[3]

IGI: Inferred from Genetic Interaction

MGI:MGI:1095403

P

From MGI

GO:0050810

regulation of steroid biosynthetic process

MGI:MGI:3769860
PMID:17495005[3]

IGI: Inferred from Genetic Interaction

MGI:MGI:1095403

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Carpenter D et al. (1998) Characterization of two patched receptors for the vertebrate hedgehog protein family. Proc Natl Acad Sci U S A 95: 13630-4 PubMed GONUTS page
  2. Chuang PT & McMahon AP (1999) Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein. Nature 397: 617-21 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 Park SY et al. (2007) Distinct roles for steroidogenic factor 1 and desert hedgehog pathways in fetal and adult Leydig cell development. Endocrinology 148: 3704-10 PubMed GONUTS page
  4. Yao HH et al. (2002) Desert Hedgehog/Patched 1 signaling specifies fetal Leydig cell fate in testis organogenesis. Genes Dev 16: 1433-40 PubMed GONUTS page
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