GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
MGI:Dhcr7
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Dhcr7 | |
| Protein Name(s) | 7-dehydrocholesterol reductase, | |
| External Links | ||
| MGI | MGI:1298378 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001568 |
blood vessel development |
MGI:MGI:3056828 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2387406 |
P |
From MGI |
||
| GO:0005640 |
nuclear outer membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005783 |
endoplasmic reticulum |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005792 |
microsome |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_071784 |
C |
From MGI |
||
| GO:0006694 |
steroid biosynthetic process |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0752 |
P |
From MGI |
||
| GO:0006695 |
cholesterol biosynthetic process |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_071784 |
P |
From MGI |
||
| GO:0006695 |
cholesterol biosynthetic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0008610 |
lipid biosynthetic process |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0444 |
P |
From MGI |
||
| GO:0009791 |
post-embryonic development |
MGI:MGI:3056828 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2387406 |
P |
From MGI |
||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016020 |
membrane |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0016021 |
integral to membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From MGI |
||
| GO:0016126 |
sterol biosynthetic process |
MGI:MGI:3056828 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2387406 |
P |
From MGI |
||
| GO:0016491 |
oxidoreductase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0560 |
F |
From MGI |
||
| GO:0016628 |
oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0030154 |
cell differentiation |
MGI:MGI:3056828 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2387406 |
P |
From MGI |
||
| GO:0030324 |
lung development |
MGI:MGI:3056828 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2387406 |
P |
From MGI |
||
| GO:0035264 |
multicellular organism growth |
MGI:MGI:3056828 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2387406 |
P |
From MGI |
||
| GO:0042127 |
regulation of cell proliferation |
MGI:MGI:3056828 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2387406 |
P |
From MGI |
||
| GO:0045540 |
regulation of cholesterol biosynthetic process |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_071784 |
P |
From MGI |
||
| GO:0047598 |
7-dehydrocholesterol reductase activity |
MGI:MGI:2157179 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0047598 |
7-dehydrocholesterol reductase activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_071784 |
F |
From MGI |
||
| GO:0047598 |
7-dehydrocholesterol reductase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Yu H et al. (2004) Late gestational lung hypoplasia in a mouse model of the Smith-Lemli-Opitz syndrome. BMC Dev Biol 4: 1 PubMed GONUTS page
- ↑ Hogenboom S et al. (2002) Absence of functional peroxisomes does not lead to deficiency of enzymes involved in cholesterol biosynthesis. J Lipid Res 43: 90-8 PubMed GONUTS page
