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MGI:Dffb

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Dffb ( synonyms: 40kDa, CAD, caspase-activated DNase, CPAN, DFF40, Didff )
Protein Name(s) DNA fragmentation factor, beta subunit,
External Links
MGI MGI:1196287

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000790

nuclear chromatin

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O76075

C

From MGI

GO:0003677

DNA binding

MGI:MGI:3574013
PMID:15572351[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0004516

nicotinate phosphoribosyltransferase activity

MGI:MGI:3574013
PMID:15572351[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0004518

nuclease activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0540

F

From MGI

GO:0004536

deoxyribonuclease activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_445814

F

From MGI

GO:0005515

protein binding

MGI:MGI:3574013
PMID:15572351[1]

IPI: Inferred from Physical Interaction

UniProtKB:O00273

F

From MGI

GO:0005622

intracellular

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR003508

C

From MGI

GO:0005634

nucleus

MGI:MGI:3574013
PMID:15572351[1]

ISO: Inferred from Sequence Orthology

UniProtKB:O76075

C

From MGI

GO:0005634

nucleus

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_445814

C

From MGI

GO:0005634

nucleus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O76075

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0963

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR015311

C

From MGI

GO:0006309

DNA fragmentation involved in apoptotic nuclear change

MGI:MGI:3574013
PMID:15572351[1]

ISO: Inferred from Sequence Orthology

UniProtKB:O76075

P

From MGI

GO:0006309

DNA fragmentation involved in apoptotic nuclear change

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_445814

P

From MGI

GO:0006915

apoptotic process

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0053

P

From MGI

GO:0006915

apoptotic process

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR003508

P

From MGI

GO:0006917

induction of apoptosis

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_445814

P

From MGI

GO:0008152

metabolic process

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0378

P

From MGI

GO:0008152

metabolic process

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR015311

P

From MGI

GO:0016787

hydrolase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0378

F

From MGI

GO:0016787

hydrolase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR015311

F

From MGI

GO:0019899

enzyme binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O76075

F

From MGI

GO:0030263

apoptotic chromosome condensation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O76075

P

From MGI

GO:0090305

nucleic acid phosphodiester bond hydrolysis

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0540

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 Korn C et al. (2005) Interaction of DNA fragmentation factor (DFF) with DNA reveals an unprecedented mechanism for nuclease inhibition and suggests that DFF can be activated in a DNA-bound state. J Biol Chem 280: 6005-15 PubMed GONUTS page
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