GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
MGI:Degs2
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Degs2 ( synonyms: Des2 ) | |
| Protein Name(s) | degenerative spermatocyte homolog 2 (Drosophila), lipid desaturase, | |
| External Links | ||
| MGI | MGI:1917309 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000170 |
sphingosine hydroxylase activity |
MGI:MGI:3056825 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0000170 |
sphingosine hydroxylase activity |
MGI:MGI:3694278 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005783 |
endoplasmic reticulum |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0256 |
C |
From MGI |
||
| GO:0006629 |
lipid metabolic process |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0006633 |
fatty acid biosynthetic process |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0006667 |
sphinganine metabolic process |
MGI:MGI:3505861 |
IGI: Inferred from Genetic Interaction |
SGD:S000002705 |
P |
From MGI |
||
| GO:0006667 |
sphinganine metabolic process |
MGI:MGI:3694278 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0008610 |
lipid biosynthetic process |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0444 |
P |
From MGI |
||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0016491 |
oxidoreductase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0560 |
F |
From MGI |
||
| GO:0016705 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0030148 |
sphingolipid biosynthetic process |
MGI:MGI:3505861 |
IGI: Inferred from Genetic Interaction |
SGD:S000002705 |
P |
From MGI |
||
| GO:0042284 |
sphingolipid delta-4 desaturase activity |
MGI:MGI:3505861 |
IGI: Inferred from Genetic Interaction |
SGD:S000002705 |
F |
From MGI |
||
| GO:0046513 |
ceramide biosynthetic process |
MGI:MGI:3694278 |
IDA: Inferred from Direct Assay |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Omae F et al. (2004) Identification of an essential sequence for dihydroceramide C-4 hydroxylase activity of mouse DES2. FEBS Lett 576: 63-7 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Enomoto A et al. (2006) Dihydroceramide:sphinganine C-4-hydroxylation requires Des2 hydroxylase and the membrane form of cytochrome b5. Biochem J 397: 289-95 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Ternes P et al. (2002) Identification and characterization of a sphingolipid delta 4-desaturase family. J Biol Chem 277: 25512-8 PubMed GONUTS page
