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MGI:Deaf1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Deaf1 ( synonyms: NUDR, suppressin )
Protein Name(s) deformed epidermal autoregulatory factor 1 (Drosophila),
External Links
MGI MGI:1858496

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001843

neural tube closure

MGI:MGI:3029622
PMID:14966286[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0003677

DNA binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0238

F

From MGI

GO:0003677

DNA binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000770

F

From MGI

GO:0005634

nucleus

MGI:MGI:4355246
PMID:19668219[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005634

nucleus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O75398

C

From MGI

GO:0005667

transcription factor complex

MGI:MGI:1321453
PMID:9860983[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4355246
PMID:19668219[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O75398

C

From MGI

GO:0006351

transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0805

P

From MGI

GO:0006357

regulation of transcription from RNA polymerase II promoter

MGI:MGI:1321453
PMID:9860983[3]

IDA: Inferred from Direct Assay

P

From MGI

GO:0006366

transcription from RNA polymerase II promoter

MGI:MGI:1321453
PMID:9860983[3]

IDA: Inferred from Direct Assay

P

From MGI

GO:0007275

multicellular organismal development

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0217

P

From MGI

GO:0007399

nervous system development

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0524

P

From MGI

GO:0008270

zinc ion binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR002893

F

From MGI

GO:0033599

regulation of mammary gland epithelial cell proliferation

MGI:MGI:3822223
PMID:18826651[4]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0033599

regulation of mammary gland epithelial cell proliferation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O75398

P

From MGI

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O88450

P

From MGI

GO:0046872

metal ion binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From MGI

GO:0048706

embryonic skeletal system development

MGI:MGI:3029622
PMID:14966286[1]

IMP: Inferred from Mutant Phenotype

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Hahm K et al. (2004) Defective neural tube closure and anteroposterior patterning in mice lacking the LIM protein LMO4 or its interacting partner Deaf-1. Mol Cell Biol 24: 2074-82 PubMed GONUTS page
  2. 2.0 2.1 Yip L et al. (2009) Deaf1 isoforms control the expression of genes encoding peripheral tissue antigens in the pancreatic lymph nodes during type 1 diabetes. Nat Immunol 10: 1026-33 PubMed GONUTS page
  3. 3.0 3.1 3.2 Sugihara TM et al. (1998) Mouse deformed epidermal autoregulatory factor 1 recruits a LIM domain factor, LMO-4, and CLIM coregulators. Proc Natl Acad Sci U S A 95: 15418-23 PubMed GONUTS page
  4. Barker HE et al. (2008) Deaf-1 regulates epithelial cell proliferation and side-branching in the mammary gland. BMC Dev Biol 8: 94 PubMed GONUTS page
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