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MGI:Ddx4
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Ddx4 ( synonyms: Mvh, mvh / m'vasa, VASA ) | |
| Protein Name(s) | DEAD (Asp-Glu-Ala-Asp) box polypeptide 4, | |
| External Links | ||
| MGI | MGI:102670 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000166 |
nucleotide binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0547 |
F |
From MGI |
||
| GO:0000237 |
leptotene |
MGI:MGI:1355402 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2182568 |
P |
From MGI |
||
| GO:0003676 |
nucleic acid binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0004386 |
helicase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0347 |
F |
From MGI |
||
| GO:0004386 |
helicase activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3655410 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:4356194 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005524 |
ATP binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0067 |
F |
From MGI |
||
| GO:0005524 |
ATP binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:2664424 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:1858321 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:2664424 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:3027482 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:3530170 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:3578091 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006200 |
ATP catabolic process |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007141 |
male meiosis I |
MGI:MGI:1355402 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2182568 |
P |
From MGI |
||
| GO:0007275 |
multicellular organismal development |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0217 |
P |
From MGI |
||
| GO:0007283 |
spermatogenesis |
MGI:MGI:1355402 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2182568 |
P |
From MGI |
||
| GO:0008026 |
ATP-dependent helicase activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0008152 |
metabolic process |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0347 |
P |
From MGI |
||
| GO:0008152 |
metabolic process |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0016787 |
hydrolase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0378 |
F |
From MGI |
||
| GO:0030317 |
sperm motility |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0030529 |
ribonucleoprotein complex |
MGI:MGI:3695528 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0032880 |
regulation of protein localization |
MGI:MGI:3695528 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2182568 |
P |
From MGI |
||
| GO:0033391 |
chromatoid body |
MGI:MGI:1858321 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0033391 |
chromatoid body |
MGI:MGI:1858321 |
ISO: Inferred from Sequence Orthology |
UniProtKB:Q5W5U4 |
C |
From MGI |
||
| GO:0044464 |
cell part |
MGI:MGI:3761040 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0048471 |
perinuclear region of cytoplasm |
MGI:MGI:1858321 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0071546 |
pi-body |
MGI:MGI:4417983 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0071547 |
piP-body |
MGI:MGI:4417983 |
IDA: Inferred from Direct Assay |
C |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Tanaka SS et al. (2000) The mouse homolog of Drosophila Vasa is required for the development of male germ cells. Genes Dev 14: 841-53 PubMed GONUTS page
- ↑ Costa Y et al. (2006) Mouse MAELSTROM: the link between meiotic silencing of unsynapsed chromatin and microRNA pathway? Hum Mol Genet 15: 2324-34 PubMed GONUTS page
- ↑ Ma L et al. (2009) GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline. PLoS Genet 5: e1000635 PubMed GONUTS page
- ↑ 4.0 4.1 McClellan KA et al. (2003) Continuous loss of oocytes throughout meiotic prophase in the normal mouse ovary. Dev Biol 258: 334-48 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 Toyooka Y et al. (2000) Expression and intracellular localization of mouse Vasa-homologue protein during germ cell development. Mech Dev 93: 139-49 PubMed GONUTS page
- ↑ Kuramochi-Miyagawa S et al. (2004) Mili, a mammalian member of piwi family gene, is essential for spermatogenesis. Development 131: 839-49 PubMed GONUTS page
- ↑ Murphy K et al. (2005) Expression of Stat3 in germ cells of developing and adult mouse ovaries and testes. Gene Expr Patterns 5: 475-82 PubMed GONUTS page
- ↑ Taketo T et al. (2005) Expression of SRY proteins in both normal and sex-reversed XY fetal mouse gonads. Dev Dyn 233: 612-22 PubMed GONUTS page
- ↑ 9.0 9.1 Hosokawa M et al. (2007) Tudor-related proteins TDRD1/MTR-1, TDRD6 and TDRD7/TRAP: domain composition, intracellular localization, and function in male germ cells in mice. Dev Biol 301: 38-52 PubMed GONUTS page
- ↑ Seandel M et al. (2007) Generation of functional multipotent adult stem cells from GPR125+ germline progenitors. Nature 449: 346-50 PubMed GONUTS page
- ↑ 11.0 11.1 Aravin AA et al. (2009) Cytoplasmic compartmentalization of the fetal piRNA pathway in mice. PLoS Genet 5: e1000764 PubMed GONUTS page
