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MGI:Ddx1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Ddx1
Protein Name(s) DEAD (Asp-Glu-Ala-Asp) box polypeptide 1,
External Links
MGI MGI:2144727

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

From MGI

GO:0003676

nucleic acid binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011545
InterPro:IPR001650

F

From MGI

GO:0003677

DNA binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0238

F

From MGI

GO:0003682

chromatin binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q92499

F

From MGI

GO:0003712

transcription cofactor activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q92499

F

From MGI

GO:0003723

RNA binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0694

F

From MGI

GO:0003725

double-stranded RNA binding

MGI:MGI:5050760
PMID:21703541[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0004386

helicase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0347

F

From MGI

GO:0004386

helicase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001650

F

From MGI

GO:0004518

nuclease activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q92499

F

From MGI

GO:0004527

exonuclease activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0269

F

From MGI

GO:0005515

protein binding

MGI:MGI:4839441
PMID:18758164[2]

IPI: Inferred from Physical Interaction

UniProtKB:P83870

F

From MGI

GO:0005515

protein binding

MGI:MGI:5050760
PMID:21703541[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q9JIK5

F

From MGI

GO:0005524

ATP binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0067

F

From MGI

GO:0005524

ATP binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011545
InterPro:IPR001650

F

From MGI

GO:0005634

nucleus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:B4DPN6

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:B4DPN6

C

From MGI

GO:0006200

ATP catabolic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q92499

P

From MGI

GO:0006302

double-strand break repair

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q92499

P

From MGI

GO:0006351

transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0805

P

From MGI

GO:0006397

mRNA processing

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0507

P

From MGI

GO:0008026

ATP-dependent helicase activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q92499

F

From MGI

GO:0008143

poly(A) RNA binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q92499

F

From MGI

GO:0009615

response to virus

MGI:MGI:5050760
PMID:21703541[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0010494

cytoplasmic stress granule

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q92499

C

From MGI

GO:0016787

hydrolase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0378

F

From MGI

GO:0030529

ribonucleoprotein complex

MGI:MGI:3822232
PMID:18809582[3]

ISO: Inferred from Sequence Orthology

UniProtKB:Q92499

C

From MGI

GO:0032508

DNA duplex unwinding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q92499

P

From MGI

GO:0033677

DNA/RNA helicase activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q92499

F

From MGI

GO:0043330

response to exogenous dsRNA

MGI:MGI:5050760
PMID:21703541[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0071920

cleavage body

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q92499

C

From MGI

GO:0072669

tRNA-splicing ligase complex

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q92499

C

From MGI

GO:0090305

nucleic acid phosphodiester bond hydrolysis

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0269

P

From MGI

GO:0090305

nucleic acid phosphodiester bond hydrolysis

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q92499

P

From MGI

GO:2001141

regulation of RNA biosynthetic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q92499

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Zhang Z et al. (2011) DDX1, DDX21, and DHX36 helicases form a complex with the adaptor molecule TRIF to sense dsRNA in dendritic cells. Immunity 34: 866-78 PubMed GONUTS page
  2. Rzymski T et al. (2008) PHF5A represents a bridge protein between splicing proteins and ATP-dependent helicases and is differentially expressed during mouse spermatogenesis. Cytogenet Genome Res 121: 232-44 PubMed GONUTS page
  3. Maggi LB Jr et al. (2008) Nucleophosmin serves as a rate-limiting nuclear export chaperone for the Mammalian ribosome. Mol Cell Biol 28: 7050-65 PubMed GONUTS page
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