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MGI:Ddit4
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Ddit4 ( synonyms: Dig2, REDD1, Rtp801 ) | |
| Protein Name(s) | DNA-damage-inducible transcript 4, | |
| External Links | ||
| MGI | MGI:1921997 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001666 |
response to hypoxia |
MGI:MGI:3773582 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0001666 |
response to hypoxia |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_543182 |
P |
From MGI |
||
| GO:0005622 |
intracellular |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005739 |
mitochondrion |
MGI:MGI:4440406 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0006915 |
apoptotic process |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_543182 |
P |
From MGI |
||
| GO:0009968 |
negative regulation of signal transduction |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0032007 |
negative regulation of TOR signaling cascade |
MGI:MGI:3773582 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0043241 |
protein complex disassembly |
MGI:MGI:3773582 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0045820 |
negative regulation of glycolysis |
MGI:MGI:4440406 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0071889 |
14-3-3 protein binding |
MGI:MGI:3773582 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0072593 |
reactive oxygen species metabolic process |
MGI:MGI:4440406 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 DeYoung MP et al. (2008) Hypoxia regulates TSC1/2-mTOR signaling and tumor suppression through REDD1-mediated 14-3-3 shuttling. Genes Dev 22: 239-51 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Horak P et al. (2010) Negative feedback control of HIF-1 through REDD1-regulated ROS suppresses tumorigenesis. Proc Natl Acad Sci U S A 107: 4675-80 PubMed GONUTS page
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