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MGI:Dct
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Dct ( synonyms: TRP-2, TRP2, tyrosinase-related protein-2, Tyrp-2, Tyrp2 ) | |
| Protein Name(s) | dopachrome tautomerase, | |
| External Links | ||
| MGI | MGI:102563 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0002052 |
positive regulation of neuroblast proliferation |
MGI:MGI:3701732 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0004167 |
dopachrome isomerase activity |
MGI:MGI:3690794 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0004167 |
dopachrome isomerase activity |
MGI:MGI:50485 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1856379 |
F |
From MGI |
||
| GO:0005737 |
cytoplasm |
MGI:MGI:5049797 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005792 |
microsome |
MGI:MGI:3690794 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005829 |
cytosol |
MGI:MGI:3690794 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0006583 |
melanin biosynthetic process from tyrosine |
MGI:MGI:3690794 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0008152 |
metabolic process |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From MGI |
||
| GO:0016491 |
oxidoreductase activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0016853 |
isomerase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0413 |
F |
From MGI |
||
| GO:0021847 |
ventricular zone neuroblast division |
MGI:MGI:3701732 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0042438 |
melanin biosynthetic process |
MGI:MGI:76308 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1856379 |
P |
From MGI |
||
| GO:0042470 |
melanosome |
MGI:MGI:3690794 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0043473 |
pigmentation |
MGI:MGI:50485 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1856379 |
P |
From MGI |
||
| GO:0046872 |
metal ion binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0479 |
F |
From MGI |
||
| GO:0048066 |
developmental pigmentation |
MGI:MGI:3041903 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1856379 |
P |
From MGI |
||
| GO:0048468 |
cell development |
MGI:MGI:3041903 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1856379 |
P |
From MGI |
||
| GO:0055114 |
oxidation-reduction process |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Jiao Z et al. (2006) Dopachrome tautomerase (Dct) regulates neural progenitor cell proliferation. Dev Biol 296: 396-408 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Aroca P et al. (1990) Regulation of mammalian melanogenesis. I: Partial purification and characterization of a dopachrome converting factor: dopachrome tautomerase. Biochim Biophys Acta 1035: 266-75 PubMed GONUTS page
- ↑ 3.0 3.1 Jackson IJ et al. (1992) A second tyrosinase-related protein, TRP-2, maps to and is mutated at the mouse slaty locus. EMBO J 11: 527-35 PubMed GONUTS page
- ↑ Agarwal P et al. (2011) The MADS box transcription factor MEF2C regulates melanocyte development and is a direct transcriptional target and partner of SOX10. Development 138: 2555-65 PubMed GONUTS page
- ↑ Ozeki H et al. (1995) Chemical characterization of hair melanins in various coat-color mutants of mice. J Invest Dermatol 105: 361-6 PubMed GONUTS page
- ↑ 6.0 6.1 Guyonneau L et al. (2004) Melanocytes and pigmentation are affected in dopachrome tautomerase knockout mice. Mol Cell Biol 24: 3396-403 PubMed GONUTS page
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