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MGI:Dcc

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Dcc ( synonyms: Igdcc1 )
Protein Name(s) deleted in colorectal carcinoma,
External Links
MGI MGI:94869

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001764

neuron migration

MGI:MGI:3607408
PMID:16267219[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1934924

P

From MGI

GO:0003713

transcription coactivator activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:Q63153

F

From MGI

GO:0005042

netrin receptor activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:Q63153

F

From MGI

GO:0005515

protein binding

MGI:MGI:3828413
PMID:11527412[2]

IPI: Inferred from Physical Interaction

UniProtKB:F8VPK3

F

From MGI

GO:0007411

axon guidance

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:Q63153

P

From MGI

GO:0010976

positive regulation of neuron projection development

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:Q63153

P

From MGI

GO:0021965

spinal cord ventral commissure morphogenesis

MGI:MGI:87114
PMID:9126737[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1934924

P

From MGI

GO:0030424

axon

MGI:MGI:1098184
PMID:9331350[4]

IDA: Inferred from Direct Assay

C

From MGI

GO:0030424

axon

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:Q63153

C

From MGI

GO:0032584

growth cone membrane

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:Q63153

C

From MGI

GO:0033563

dorsal/ventral axon guidance

MGI:MGI:3758130
PMID:17898206[5]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1934924

P

From MGI

GO:0038007

netrin-activated signaling pathway

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:Q63153

P

From MGI

GO:0042802

identical protein binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:Q63153

F

From MGI

GO:0045121

membrane raft

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:Q63153

C

From MGI

GO:0070374

positive regulation of ERK1 and ERK2 cascade

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:Q63153

P

From MGI

GO:2001141

regulation of RNA biosynthetic process

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:Q63155

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Dillon AK et al. (2005) Molecular control of spinal accessory motor neuron/axon development in the mouse spinal cord. J Neurosci 25: 10119-30 PubMed GONUTS page
  2. Ugai H et al. (2001) Interaction of Myc-associated zinc finger protein with DCC, the product of a tumor-suppressor gene, during the neural differentiation of P19 EC cells. Biochem Biophys Res Commun 286: 1087-97 PubMed GONUTS page
  3. Fazeli A et al. (1997) Phenotype of mice lacking functional Deleted in colorectal cancer (Dcc) gene. Nature 386: 796-804 PubMed GONUTS page
  4. Deiner MS et al. (1997) Netrin-1 and DCC mediate axon guidance locally at the optic disc: loss of function leads to optic nerve hypoplasia. Neuron 19: 575-89 PubMed GONUTS page
  5. Ren T et al. (2007) Diffusion tensor magnetic resonance imaging and tract-tracing analysis of Probst bundle structure in Netrin1- and DCC-deficient mice. J Neurosci 27: 10345-9 PubMed GONUTS page
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