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MGI:Daxx
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Daxx | |
| Protein Name(s) | Fas death domain-associated protein, | |
| External Links | ||
| MGI | MGI:1197015 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000281 |
cytokinesis after mitosis |
MGI:MGI:3051070 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3051780 |
P |
From MGI |
||
| GO:0000792 |
heterochromatin |
MGI:MGI:3051070 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0002039 |
p53 binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0003713 |
transcription coactivator activity |
MGI:MGI:3688031 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003714 |
transcription corepressor activity |
MGI:MGI:3688031 |
TAS: Traceable Author Statement |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:2449749 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3051070 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3583841 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3687891 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3688031 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:4839460 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:4942266 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:893321 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:2449749 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3583841 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_543167 |
C |
From MGI |
||
| GO:0005634 |
nucleus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_543167 |
C |
From MGI |
||
| GO:0005829 |
cytosol |
MGI:MGI:4942266 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005938 |
cell cortex |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_543167 |
C |
From MGI |
||
| GO:0006351 |
transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0804 |
P |
From MGI |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:3583841 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006915 |
apoptotic process |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0053 |
P |
From MGI |
||
| GO:0006917 |
induction of apoptosis |
MGI:MGI:4942266 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0008134 |
transcription factor binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0016605 |
PML body |
MGI:MGI:2178905 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0016605 |
PML body |
MGI:MGI:2449749 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0016605 |
PML body |
MGI:MGI:3051070 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0016605 |
PML body |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0016605 |
PML body |
MGI:MGI:4942266 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0019899 |
enzyme binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0030521 |
androgen receptor signaling pathway |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0031396 |
regulation of protein ubiquitination |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0031625 |
ubiquitin protein ligase binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0042803 |
protein homodimerization activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0043005 |
neuron projection |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_543167 |
C |
From MGI |
||
| GO:0044297 |
cell body |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_543167 |
C |
From MGI |
||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
MGI:MGI:2449749 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0047485 |
protein N-terminus binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0050681 |
androgen receptor binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:2001141 |
regulation of RNA biosynthetic process |
MGI:MGI:3688031 |
TAS: Traceable Author Statement |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Ishov AM et al. (2004) Heterochromatin and ND10 are cell-cycle regulated and phosphorylation-dependent alternate nuclear sites of the transcription repressor Daxx and SWI/SNF protein ATRX. J Cell Sci 117: 3807-20 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Emelyanov AV et al. (2002) The interaction of Pax5 (BSAP) with Daxx can result in transcriptional activation in B cells. J Biol Chem 277: 11156-64 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Ecsedy JA et al. (2003) Homeodomain-interacting protein kinase 1 modulates Daxx localization, phosphorylation, and transcriptional activity. Mol Cell Biol 23: 950-60 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Tang J et al. (2005) The death domain-associated protein modulates activity of the transcription co-factor Skip/NcoA62. FEBS Lett 579: 2883-90 PubMed GONUTS page
- ↑ Kawai T et al. (2003) ZIP kinase triggers apoptosis from nuclear PML oncogenic domains. Mol Cell Biol 23: 6174-86 PubMed GONUTS page
- ↑ Perlman R et al. (2001) TGF-beta-induced apoptosis is mediated by the adapter protein Daxx that facilitates JNK activation. Nat Cell Biol 3: 708-14 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 7.3 Zhong S et al. (2000) Promyelocytic leukemia protein (PML) and Daxx participate in a novel nuclear pathway for apoptosis. J Exp Med 191: 631-40 PubMed GONUTS page
- ↑ Yang X et al. (1997) Daxx, a novel Fas-binding protein that activates JNK and apoptosis. Cell 89: 1067-76 PubMed GONUTS page
- ↑ Lopez P et al. (2002) Gene control in germinal differentiation: RNF6, a transcription regulatory protein in the mouse sertoli cell. Mol Cell Biol 22: 3488-96 PubMed GONUTS page
