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MGI:Dapk3

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Dapk3 ( synonyms: ZIP kinase )
Protein Name(s) death-associated protein kinase 3,
External Links
MGI MGI:1203520

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

From MGI

GO:0000775

chromosome, centromeric region

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0137

C

From MGI

GO:0004672

protein kinase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR002290

F

From MGI

GO:0004674

protein serine/threonine kinase activity

MGI:MGI:1196722
PMID:9488481[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0004674

protein serine/threonine kinase activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O88209

F

From MGI

GO:0004674

protein serine/threonine kinase activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O43293

F

From MGI

GO:0005515

protein binding

MGI:MGI:3687891
PMID:12917339[2]

IPI: Inferred from Physical Interaction

UniProtKB:O35613
UniProtKB:Q925B0

F

From MGI

GO:0005524

ATP binding

MGI:MGI:1196722
PMID:9488481[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005524

ATP binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O88209

F

From MGI

GO:0005524

ATP binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O43293

F

From MGI

GO:0005634

nucleus

MGI:MGI:1196722
PMID:9488481[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005634

nucleus

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O88209

C

From MGI

GO:0005694

chromosome

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0158

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0963

C

From MGI

GO:0005856

cytoskeleton

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0206

C

From MGI

GO:0006351

transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0805

P

From MGI

GO:0006468

protein phosphorylation

MGI:MGI:1196722
PMID:9488481[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0006468

protein phosphorylation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O43293

P

From MGI

GO:0006915

apoptotic process

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0053

P

From MGI

GO:0006917

induction of apoptosis

MGI:MGI:1196722
PMID:9488481[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0006917

induction of apoptosis

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O88209

P

From MGI

GO:0006917

induction of apoptosis

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O43293

P

From MGI

GO:0007243

intracellular protein kinase cascade

MGI:MGI:1196722
PMID:9488481[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0007243

intracellular protein kinase cascade

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O88209

P

From MGI

GO:0007243

intracellular protein kinase cascade

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O43293

P

From MGI

GO:0016301

kinase activity

MGI:MGI:3796498
PMID:18310078[3]

ISO: Inferred from Sequence Orthology

UniProtKB:O88209

F

From MGI

GO:0016310

phosphorylation

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

P

From MGI

GO:0016568

chromatin modification

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0156

P

From MGI

GO:0016740

transferase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0808

F

From MGI

GO:0016772

transferase activity, transferring phosphorus-containing groups

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011009

F

From MGI

GO:0030182

neuron differentiation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O88209

P

From MGI

GO:0042803

protein homodimerization activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O43293

F

From MGI

GO:0042803

protein homodimerization activity

MGI:MGI:5294292
PMID:18239682[4]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:O43293

F

From MGI

GO:0043522

leucine zipper domain binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O43293

F

From MGI

GO:0046777

protein autophosphorylation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O43293

P

From MGI

GO:0046777

protein autophosphorylation

MGI:MGI:5294292
PMID:18239682[4]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:O43293

P

From MGI

GO:0090263

positive regulation of canonical Wnt receptor signaling pathway

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O43293

P

From MGI

GO:2001241

positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O88209

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 1.5 Kawai T et al. (1998) ZIP kinase, a novel serine/threonine kinase which mediates apoptosis. Mol Cell Biol 18: 1642-51 PubMed GONUTS page
  2. Kawai T et al. (2003) ZIP kinase triggers apoptosis from nuclear PML oncogenic domains. Mol Cell Biol 23: 6174-86 PubMed GONUTS page
  3. Wooldridge AA et al. (2008) Deletion of the protein kinase A/protein kinase G target SMTNL1 promotes an exercise-adapted phenotype in vascular smooth muscle. J Biol Chem 283: 11850-9 PubMed GONUTS page
  4. 4.0 4.1 Pike AC et al. (2008) Activation segment dimerization: a mechanism for kinase autophosphorylation of non-consensus sites. EMBO J 27: 704-14 PubMed GONUTS page
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