Ambox notice.png

GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.

You can help reduce stress on the server by:

  1. not reloading pages frequently - this just adds
  2. opening links in new windows (so you can read the old page)

MGI:Dand5

From GONUTS
Jump to: navigation, search

Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Dand5 ( synonyms: Cerl-2, Cerr2, coco, Dte )
Protein Name(s) DAN domain family, member 5,
External Links
MGI MGI:1344365

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003140

determination of left/right asymmetry in lateral mesoderm

MGI:MGI:3055649
PMID:15466485[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0003281

ventricular septum development

MGI:MGI:3055649
PMID:15466485[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0003283

atrial septum development

MGI:MGI:3055649
PMID:15466485[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0005515

protein binding

MGI:MGI:3055649
PMID:15466485[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q91619

F

From MGI

GO:0005576

extracellular region

MGI:MGI:3055649
PMID:15466485[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005576

extracellular region

MGI:MGI:3055649
PMID:15466485[1]

NAS: Non-traceable Author Statement

C

From MGI

GO:0007368

determination of left/right symmetry

MGI:MGI:3055649
PMID:15466485[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:97359

P

From MGI

GO:0007368

determination of left/right symmetry

MGI:MGI:3055649
PMID:15466485[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3056132

P

From MGI

GO:0016015

morphogen activity

MGI:MGI:3055649
PMID:15466485[1]

IMP: Inferred from Mutant Phenotype

F

From MGI

GO:0017015

regulation of transforming growth factor beta receptor signaling pathway

MGI:MGI:1335654
PMID:10208746[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0030512

negative regulation of transforming growth factor beta receptor signaling pathway

MGI:MGI:3055566
PMID:14721776[3]

IGI: Inferred from Genetic Interaction

MGI:MGI:97359

P

From MGI

GO:0030514

negative regulation of BMP signaling pathway

MGI:MGI:3055649
PMID:15466485[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0038101

sequestering of nodal from receptor via nodal binding

MGI:MGI:3055649
PMID:15466485[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0061371

determination of heart left/right asymmetry

MGI:MGI:3055649
PMID:15466485[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:1900108

negative regulation of nodal signaling pathway

MGI:MGI:3055649
PMID:15466485[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:1900164

nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry

MGI:MGI:5315339
PMID:17507406[4]

NAS: Non-traceable Author Statement

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 Marques S et al. (2004) The activity of the Nodal antagonist Cerl-2 in the mouse node is required for correct L/R body axis. Genes Dev 18: 2342-7 PubMed GONUTS page
  2. Pearce JJ et al. (1999) A mouse cerberus/Dan-related gene family. Dev Biol 209: 98-110 PubMed GONUTS page
  3. Mastrangeli R et al. (2003) ARS Component B: structural characterization, tissue expression and regulation of the gene and protein (SLURP-1) associated with Mal de Meleda. Eur J Dermatol 13: 560-70 PubMed GONUTS page
  4. Tavares AT et al. (2007) Cerberus is a feedback inhibitor of Nodal asymmetric signaling in the chick embryo. Development 134: 2051-60 PubMed GONUTS page
Personal tools
Namespaces
Variants
Actions
Navigation
Cacao
Journal Clubs
page contributors
Toolbox