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MGI:Dach1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Dach1 ( synonyms: Dac ) | |
| Protein Name(s) | dachshund 1 (Drosophila), | |
| External Links | ||
| MGI | MGI:1277991 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
MGI:MGI:3719935 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
MGI:MGI:3719935 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:96646 |
P |
From MGI |
||
| GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
MGI:MGI:4850233 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2448366 |
P |
From MGI |
||
| GO:0000166 |
nucleotide binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0001075 |
RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly |
MGI:MGI:4850233 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0001078 |
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0001967 |
suckling behavior |
MGI:MGI:1930429 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2182311 |
P |
From MGI |
||
| GO:0003677 |
DNA binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0238 |
F |
From MGI |
||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
MGI:MGI:2680872 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:1926539 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3611682 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:1926539 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:2149901 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:2386381 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3608542 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005667 |
transcription factor complex |
MGI:MGI:2680872 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005667 |
transcription factor complex |
MGI:MGI:3719935 |
IPI: Inferred from Physical Interaction |
UniProtKB:O09106 |
C |
From MGI |
||
| GO:0005730 |
nucleolus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:1926539 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:3608542 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0006351 |
transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0804 |
P |
From MGI |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:2680872 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:2680872 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0007275 |
multicellular organismal development |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0217 |
P |
From MGI |
||
| GO:0007585 |
respiratory gaseous exchange |
MGI:MGI:1930429 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2182311 |
P |
From MGI |
||
| GO:0008283 |
cell proliferation |
MGI:MGI:4850233 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2448366 |
P |
From MGI |
||
| GO:0010944 |
negative regulation of transcription by competitive promoter binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0030336 |
negative regulation of cell migration |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0046545 |
development of primary female sexual characteristics |
MGI:MGI:3790571 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1890446 |
P |
From MGI |
||
| GO:0048147 |
negative regulation of fibroblast proliferation |
MGI:MGI:3719935 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0048147 |
negative regulation of fibroblast proliferation |
MGI:MGI:3719935 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:96646 |
P |
From MGI |
||
| GO:0051123 |
RNA polymerase II transcriptional preinitiation complex assembly |
MGI:MGI:4850233 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0060244 |
negative regulation of cell proliferation involved in contact inhibition |
MGI:MGI:3719935 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:96646 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Wu K et al. (2007) Cell fate determination factor DACH1 inhibits c-Jun-induced contact-independent growth. Mol Biol Cell 18: 755-67 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Kalousova A et al. (2010) Dachshund homologues play a conserved role in islet cell development. Dev Biol 348: 143-52 PubMed GONUTS page
- ↑ 3.0 3.1 Davis RJ et al. (2001) Dach1 mutant mice bear no gross abnormalities in eye, limb, and brain development and exhibit postnatal lethality. Mol Cell Biol 21: 1484-90 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 Li X et al. (2003) Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesis. Nature 426: 247-54 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 Machon O et al. (2000) Yeast two-hybrid system identifies the ubiquitin-conjugating enzyme mUbc9 as a potential partner of mouse Dac. Mech Dev 97: 3-12 PubMed GONUTS page
- ↑ Li X et al. (2002) Tissue-specific regulation of retinal and pituitary precursor cell proliferation. Science 297: 1180-3 PubMed GONUTS page
- ↑ Ayres JA et al. (2001) DACH: genomic characterization, evaluation as a candidate for postaxial polydactyly type A2, and developmental expression pattern of the mouse homologue. Genomics 77: 18-26 PubMed GONUTS page
- ↑ Horner A et al. (2002) Fibroblast growth factor signaling regulates Dach1 expression during skeletal development. Dev Dyn 225: 35-45 PubMed GONUTS page
- ↑ 9.0 9.1 Purcell P et al. (2005) Pax6-dependence of Six3, Eya1 and Dach1 expression during lens and nasal placode induction. Gene Expr Patterns 6: 110-8 PubMed GONUTS page
- ↑ Davis RJ et al. (2008) Mouse Dach1 and Dach2 are redundantly required for Müllerian duct development. Genesis 46: 205-13 PubMed GONUTS page
