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MGI:Cyp7b1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Cyp7b1 ( synonyms: D3Ertd552e, hct-1 )
Protein Name(s) cytochrome P450, family 7, subfamily b, polypeptide 1,
External Links
MGI MGI:104978

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004497

monooxygenase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0503

F

From MGI

GO:0004497

monooxygenase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR002403

F

From MGI

GO:0005506

iron ion binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001128
InterPro:IPR002403

F

From MGI

GO:0005783

endoplasmic reticulum

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0256

C

From MGI

GO:0005792

microsome

MGI:MGI:1859119
PMID:10748047[1]

TAS: Traceable Author Statement

C

From MGI

GO:0006629

lipid metabolic process

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0443

P

From MGI

GO:0006699

bile acid biosynthetic process

MGI:MGI:1859119
PMID:10748047[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0007586

digestion

MGI:MGI:1859119
PMID:10748047[1]

TAS: Traceable Author Statement

P

From MGI

GO:0007613

memory

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:Q63688

P

From MGI

GO:0007623

circadian rhythm

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:Q63688

P

From MGI

GO:0008202

steroid metabolic process

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0753

P

From MGI

GO:0008203

cholesterol metabolic process

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0153

P

From MGI

GO:0008396

oxysterol 7-alpha-hydroxylase activity

MGI:MGI:1859119
PMID:10748047[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0009055

electron carrier activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001128

F

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016491

oxidoreductase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0560

F

From MGI

GO:0016705

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001128
InterPro:IPR002403

F

From MGI

GO:0020037

heme binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001128
InterPro:IPR002403

F

From MGI

GO:0033147

negative regulation of intracellular estrogen receptor signaling pathway

MGI:MGI:3761900
PMID:12370428[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2182328

P

From MGI

GO:0033783

25-hydroxycholesterol 7alpha-hydroxylase activity

MGI:MGI:2152096

IEA: Inferred from Electronic Annotation

EC:1.14.13.100

F

From MGI

GO:0046872

metal ion binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From MGI

GO:0050679

positive regulation of epithelial cell proliferation

MGI:MGI:3761900
PMID:12370428[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2182328

P

From MGI

GO:0055114

oxidation-reduction process

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0560

P

From MGI

GO:0055114

oxidation-reduction process

MGI:MGI:1859119
PMID:10748047[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0055114

oxidation-reduction process

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001128
InterPro:IPR002403

P

From MGI

GO:0060740

prostate gland epithelium morphogenesis

MGI:MGI:3761900
PMID:12370428[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2182328

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 Li-Hawkins J et al. (2000) Expression cloning of an oxysterol 7alpha-hydroxylase selective for 24-hydroxycholesterol. J Biol Chem 275: 16543-9 PubMed GONUTS page
  2. 2.0 2.1 2.2 Weihua Z et al. (2002) An endocrine pathway in the prostate, ERbeta, AR, 5alpha-androstane-3beta,17beta-diol, and CYP7B1, regulates prostate growth. Proc Natl Acad Sci U S A 99: 13589-94 PubMed GONUTS page
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