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MGI:Cybb

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Cybb ( synonyms: Cgd, gp91, gp91phox, Nox2 )
Protein Name(s) cytochrome b-245, beta polypeptide,
External Links
MGI MGI:88574

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005216

ion channel activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0407

F

From MGI

GO:0005244

voltage-gated ion channel activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0851

F

From MGI

GO:0005506

iron ion binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR013130

F

From MGI

GO:0005622

intracellular

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_076455

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:3576833
PMID:15850784[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:3610800
PMID:15499027[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005739

mitochondrion

MGI:MGI:2682130
PMID:14651853[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005783

endoplasmic reticulum

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_076455

C

From MGI

GO:0005791

rough endoplasmic reticulum

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_076455

C

From MGI

GO:0005794

Golgi apparatus

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_076455

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:3610800
PMID:15499027[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_076455

C

From MGI

GO:0005887

integral to plasma membrane

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04839

C

From MGI

GO:0006801

superoxide metabolic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04839

P

From MGI

GO:0006810

transport

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0813

P

From MGI

GO:0006811

ion transport

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0406

P

From MGI

GO:0009055

electron carrier activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR013130

F

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016020

membrane

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000778

C

From MGI

GO:0016021

integral to membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0812

C

From MGI

GO:0016021

integral to membrane

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR013130

C

From MGI

GO:0016491

oxidoreductase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0560

F

From MGI

GO:0016491

oxidoreductase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000778
InterPro:IPR013112
InterPro:IPR017927
InterPro:IPR013121
InterPro:IPR013130
InterPro:IPR017938

F

From MGI

GO:0020037

heme binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04839

F

From MGI

GO:0022900

electron transport chain

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0249

P

From MGI

GO:0030425

dendrite

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_076455

C

From MGI

GO:0034765

regulation of ion transmembrane transport

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0851

P

From MGI

GO:0042493

response to drug

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_076455

P

From MGI

GO:0042554

superoxide anion generation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04839

P

From MGI

GO:0043020

NADPH oxidase complex

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_076455

C

From MGI

GO:0043020

NADPH oxidase complex

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04839

C

From MGI

GO:0043025

neuronal cell body

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_076455

C

From MGI

GO:0045087

innate immune response

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04839

P

From MGI

GO:0045730

respiratory burst

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04839

P

From MGI

GO:0046872

metal ion binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From MGI

GO:0046982

protein heterodimerization activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04839

F

From MGI

GO:0050660

flavin adenine dinucleotide binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04839

F

From MGI

GO:0050665

hydrogen peroxide biosynthetic process

MGI:MGI:3050718
PMID:15258578[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857284

P

From MGI

GO:0055114

oxidation-reduction process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04839

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Shukla S et al. (2005) Identification of non-mitochondrial NADPH oxidase and the spatio-temporal organization of its components in mouse spermatozoa. Biochem Biophys Res Commun 331: 476-83 PubMed GONUTS page
  2. 2.0 2.1 Kazama K et al. (2004) Angiotensin II impairs neurovascular coupling in neocortex through NADPH oxidase-derived radicals. Circ Res 95: 1019-26 PubMed GONUTS page
  3. Mootha VK et al. (2003) Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Cell 115: 629-40 PubMed GONUTS page
  4. Jackson SH et al. (2004) T cells express a phagocyte-type NADPH oxidase that is activated after T cell receptor stimulation. Nat Immunol 5: 818-27 PubMed GONUTS page
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