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MGI:Cyb5r4
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Cyb5r4 ( synonyms: B5+B5R, b5/b5r, Ncb5or ) | |
| Protein Name(s) | cytochrome b5 reductase 4, | |
| External Links | ||
| MGI | MGI:2386848 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003958 |
NADPH-hemoprotein reductase activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_596918 |
F |
From MGI |
||
| GO:0004128 |
cytochrome-b5 reductase activity |
MGI:MGI:1350883 |
ISA: Inferred from Sequence Alignment |
EMBL:AF169803 |
F |
From MGI |
||
| GO:0004128 |
cytochrome-b5 reductase activity |
MGI:MGI:3047531 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0004128 |
cytochrome-b5 reductase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3040580 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005623 |
cell |
MGI:MGI:3047191 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3050973 |
C |
From MGI |
||
| GO:0005737 |
cytoplasm |
MGI:MGI:1350883 |
ISA: Inferred from Sequence Alignment |
EMBL:AF169803 |
C |
From MGI |
||
| GO:0005783 |
endoplasmic reticulum |
MGI:MGI:3047531 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005783 |
endoplasmic reticulum |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006091 |
generation of precursor metabolites and energy |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006739 |
NADP metabolic process |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_596918 |
P |
From MGI |
||
| GO:0006801 |
superoxide metabolic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0016174 |
NAD(P)H oxidase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0016491 |
oxidoreductase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0560 |
F |
From MGI |
||
| GO:0016491 |
oxidoreductase activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
InterPro:IPR017927 |
F |
From MGI |
||
| GO:0016653 |
oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0020037 |
heme binding |
MGI:MGI:1350883 |
ISA: Inferred from Sequence Alignment |
EMBL:AF169803 |
F |
From MGI |
||
| GO:0020037 |
heme binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_596918 |
F |
From MGI |
||
| GO:0030073 |
insulin secretion |
MGI:MGI:3047191 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3050973 |
P |
From MGI |
||
| GO:0042168 |
heme metabolic process |
MGI:MGI:1350883 |
ISA: Inferred from Sequence Alignment |
EMBL:AF169803 |
P |
From MGI |
||
| GO:0042593 |
glucose homeostasis |
MGI:MGI:3047191 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3050973 |
P |
From MGI |
||
| GO:0046677 |
response to antibiotic |
MGI:MGI:3715661 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3050973 |
P |
From MGI |
||
| GO:0046872 |
metal ion binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0479 |
F |
From MGI |
||
| GO:0048468 |
cell development |
MGI:MGI:3047191 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3050973 |
P |
From MGI |
||
| GO:0048471 |
perinuclear region of cytoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0050660 |
flavin adenine dinucleotide binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_596918 |
F |
From MGI |
||
| GO:0055114 |
oxidation-reduction process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Zhu H et al. (1999) Identification of a cytochrome b-type NAD(P)H oxidoreductase ubiquitously expressed in human cells. Proc Natl Acad Sci U S A 96: 14742-7 PubMed GONUTS page
- ↑ 2.0 2.1 Zhu H et al. (2004) NCB5OR is a novel soluble NAD(P)H reductase localized in the endoplasmic reticulum. J Biol Chem 279: 30316-25 PubMed GONUTS page
- ↑ Oikawa K et al. (2004) Neuronal calcium sensor protein visinin-like protein-3 interacts with microsomal cytochrome b5 in a Ca2+-dependent manner. J Biol Chem 279: 15142-52 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 Xie J et al. (2004) Absence of a reductase, NCB5OR, causes insulin-deficient diabetes. Proc Natl Acad Sci U S A 101: 10750-5 PubMed GONUTS page
- ↑ Larade K et al. (2007) The reductase NCB5OR is responsive to the redox status in beta-cells and is not involved in the ER stress response. Biochem J 404: 467-76 PubMed GONUTS page
